HCSGD entry for NCKAP1
1. General information
| Official gene symbol | NCKAP1 |
|---|---|
| Entrez ID | 10787 |
| Gene full name | NCK-associated protein 1 |
| Other gene symbols | HEM2 NAP1 NAP125 p125Nap1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001701 | In utero embryonic development | IEA | biological_process |
| GO:0001756 | Somitogenesis | IEA | biological_process |
| GO:0001843 | Neural tube closure | IEA | biological_process |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0006915 | Apoptotic process | TAS | biological_process |
| GO:0007354 | Zygotic determination of anterior/posterior axis, embryo | IEA | biological_process |
| GO:0007417 | Central nervous system development | TAS | biological_process |
| GO:0007492 | Endoderm development | IEA | biological_process |
| GO:0008078 | Mesodermal cell migration | IEA | biological_process |
| GO:0010172 | Embryonic body morphogenesis | IEA | biological_process |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0030032 | Lamellipodium assembly | IEA | biological_process |
| GO:0030950 | Establishment or maintenance of actin cytoskeleton polarity | IEA | biological_process |
| GO:0031258 | Lamellipodium membrane | IEA | cellular_component |
| GO:0032880 | Regulation of protein localization | IEA | biological_process |
| GO:0035050 | Embryonic heart tube development | IEA | biological_process |
| GO:0038096 | Fc-gamma receptor signaling pathway involved in phagocytosis | TAS | biological_process |
| GO:0045087 | Innate immune response | TAS | biological_process |
| GO:0045175 | Basal protein localization | IEA | biological_process |
| GO:0045176 | Apical protein localization | IEA | biological_process |
| GO:0048340 | Paraxial mesoderm morphogenesis | IEA | biological_process |
| GO:0048570 | Notochord morphogenesis | IEA | biological_process |
| GO:0048617 | Embryonic foregut morphogenesis | IEA | biological_process |
| GO:0050821 | Protein stabilization | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.3235294480 | 0.2086923217 | 0.9999902473 | 0.8843123371 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1362182407 |
| GSE13712_SHEAR | Down | -0.0813078593 |
| GSE13712_STATIC | Up | 0.2287415275 |
| GSE19018 | Up | 0.3820954085 |
| GSE19899_A1 | Down | -0.1245225620 |
| GSE19899_A2 | Down | -0.4198148473 |
| PubMed_21979375_A1 | Down | -0.1117810435 |
| PubMed_21979375_A2 | Down | -0.5940144727 |
| GSE35957 | Up | 0.7903705192 |
| GSE36640 | Up | 0.4067031919 |
| GSE54402 | Down | -0.0440592844 |
| GSE9593 | Up | 0.2212488061 |
| GSE43922 | Down | -0.0308557035 |
| GSE24585 | Down | -0.0529288083 |
| GSE37065 | Down | -0.0066541593 |
| GSE28863_A1 | Up | 0.1603329698 |
| GSE28863_A2 | Up | 0.7083422237 |
| GSE28863_A3 | Down | -0.2994511096 |
| GSE28863_A4 | Down | -0.3418176021 |
| GSE48662 | Down | -0.3031616487 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-155-5p | MIMAT0000646 | MIRT020619 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-142-3p | MIMAT0000434 | MIRT021593 | Microarray | Functional MTI (Weak) | 17612493 |
| hsa-miR-30a-5p | MIMAT0000087 | MIRT028458 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-18b-5p | MIMAT0001412 | MIRT042408 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-132-3p | MIMAT0000426 | MIRT045845 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
