HCSGD entry for WDR4
1. General information
| Official gene symbol | WDR4 |
|---|---|
| Entrez ID | 10785 |
| Gene full name | WD repeat domain 4 |
| Other gene symbols | TRM82 TRMT82 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001510 | RNA methylation | IDA | biological_process |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005654 | Nucleoplasm | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0006400 | TRNA modification | IDA | biological_process |
| GO:0008176 | TRNA (guanine-N7-)-methyltransferase activity | IDA | molecular_function |
| GO:0030488 | TRNA methylation | IDA | biological_process |
| GO:0032259 | Methylation | IDA | biological_process |
| GO:0036265 | RNA (guanine-N7)-methylation | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9277834353 | 0.0137022795 | 0.9999902473 | 0.2304522045 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0870010409 |
| GSE13712_SHEAR | Up | 0.2176442685 |
| GSE13712_STATIC | Up | 0.2259196113 |
| GSE19018 | Down | -0.7790520221 |
| GSE19899_A1 | Down | -0.3705978803 |
| GSE19899_A2 | Down | -0.5406798602 |
| PubMed_21979375_A1 | Up | 0.2925249040 |
| PubMed_21979375_A2 | Down | -1.0757153074 |
| GSE35957 | Down | -0.4791016286 |
| GSE36640 | Down | -0.6206667850 |
| GSE54402 | Up | 0.2111422055 |
| GSE9593 | Down | -0.7976251130 |
| GSE43922 | Down | -0.0290121813 |
| GSE24585 | Down | -1.1336643546 |
| GSE37065 | Down | -0.2166445932 |
| GSE28863_A1 | Up | 0.1122974121 |
| GSE28863_A2 | Down | -0.0089230421 |
| GSE28863_A3 | Up | 0.0004959969 |
| GSE28863_A4 | Up | 0.1033809215 |
| GSE48662 | Down | -0.4396585752 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-26b-5p | MIMAT0000083 | MIRT029098 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-let-7b-5p | MIMAT0000063 | MIRT032196 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-877-3p | MIMAT0004950 | MIRT036980 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-615-3p | MIMAT0003283 | MIRT039661 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-484 | MIMAT0002174 | MIRT041960 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-100-5p | MIMAT0000098 | MIRT048521 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7e-5p | MIMAT0000066 | MIRT051666 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
