HCSGD entry for AHCYL1
1. General information
| Official gene symbol | AHCYL1 |
|---|---|
| Entrez ID | 10768 |
| Gene full name | adenosylhomocysteinase-like 1 |
| Other gene symbols | DCAL IRBIT PRO0233 XPVKONA |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004013 | Adenosylhomocysteinase activity | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005783 | Endoplasmic reticulum | IEA | cellular_component |
| GO:0006378 | MRNA polyadenylation | IEA | biological_process |
| GO:0006611 | Protein export from nucleus | IEA | biological_process |
| GO:0006730 | One-carbon metabolic process | IEA | biological_process |
| GO:0010765 | Positive regulation of sodium ion transport | IEA | biological_process |
| GO:0031440 | Regulation of mRNA 3'-end processing | IEA | biological_process |
| GO:0032412 | Regulation of ion transmembrane transporter activity | IEA | biological_process |
| GO:0044070 | Regulation of anion transport | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.4490830136 | 0.5310515254 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0201218419 |
| GSE13712_SHEAR | Down | -0.1938816747 |
| GSE13712_STATIC | Down | -0.0187193956 |
| GSE19018 | Up | 0.0689484737 |
| GSE19899_A1 | Up | 0.3310108841 |
| GSE19899_A2 | Down | -0.2424226678 |
| PubMed_21979375_A1 | Down | -0.4459574278 |
| PubMed_21979375_A2 | Up | 0.0699034473 |
| GSE35957 | Down | -0.3622250101 |
| GSE36640 | Up | 0.2748482431 |
| GSE54402 | Up | 0.1221580039 |
| GSE9593 | Down | -0.2330171515 |
| GSE43922 | - | - |
| GSE24585 | - | - |
| GSE37065 | - | - |
| GSE28863_A1 | Up | 0.2202973124 |
| GSE28863_A2 | Up | 0.4547998007 |
| GSE28863_A3 | Down | -0.4132526279 |
| GSE28863_A4 | Down | -0.2025641109 |
| GSE48662 | Up | 0.3613938774 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-375 | MIMAT0000728 | MIRT019871 | Microarray | Functional MTI (Weak) | 20215506 |
| hsa-miR-16-5p | MIMAT0000069 | MIRT031633 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-1229-3p | MIMAT0005584 | MIRT036279 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-92a-3p | MIMAT0000092 | MIRT049333 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7b-5p | MIMAT0000063 | MIRT052133 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
