HCSGD entry for AP4B1
1. General information
| Official gene symbol | AP4B1 |
|---|---|
| Entrez ID | 10717 |
| Gene full name | adaptor-related protein complex 4, beta 1 subunit |
| Other gene symbols | BETA-4 CPSQ5 SPG47 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005215 | Transporter activity | TAS | molecular_function |
| GO:0005794 | Golgi apparatus | IEA | cellular_component |
| GO:0005802 | Trans-Golgi network | IEA | cellular_component |
| GO:0005905 | Coated pit | IEA | cellular_component |
| GO:0006886 | Intracellular protein transport | IEA | biological_process |
| GO:0008565 | Protein transporter activity | IEA | molecular_function |
| GO:0016192 | Vesicle-mediated transport | IEA | biological_process |
| GO:0030117 | Membrane coat | IEA | cellular_component |
| GO:0030131 | Clathrin adaptor complex | IEA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.6142114927 | 0.4959454808 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.2072571949 |
| GSE13712_SHEAR | Up | 0.0503749942 |
| GSE13712_STATIC | Up | 0.1679295290 |
| GSE19018 | Down | -0.0994887125 |
| GSE19899_A1 | Up | 0.1239716849 |
| GSE19899_A2 | Up | 0.0475876831 |
| PubMed_21979375_A1 | Down | -0.0847172657 |
| PubMed_21979375_A2 | Down | -0.1524631041 |
| GSE35957 | Down | -0.2525462879 |
| GSE36640 | Down | -0.0479301915 |
| GSE54402 | Down | -0.0234617703 |
| GSE9593 | Down | -0.1468280551 |
| GSE43922 | Up | 0.1411008293 |
| GSE24585 | Down | -0.1022966215 |
| GSE37065 | Up | 0.2674702192 |
| GSE28863_A1 | Up | 0.1102001058 |
| GSE28863_A2 | Up | 0.4504540857 |
| GSE28863_A3 | Down | -0.7136201649 |
| GSE28863_A4 | Down | -0.0662390783 |
| GSE48662 | Down | -0.3653244528 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-378a-5p | MIMAT0000731 | MIRT043998 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-23b-3p | MIMAT0000418 | MIRT046304 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
