HCSGD entry for FAM189B
1. General information
| Official gene symbol | FAM189B |
|---|---|
| Entrez ID | 10712 |
| Gene full name | family with sequence similarity 189, member B |
| Other gene symbols | C1orf2 COTE1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0008150 | Biological_process | ND | biological_process |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0050699 | WW domain binding | IPI | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0244348961 | 0.8932921622 | 0.3697761494 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.3395077406 |
| GSE13712_SHEAR | Down | -0.0398535540 |
| GSE13712_STATIC | Up | 0.2572205302 |
| GSE19018 | Up | 0.4158345167 |
| GSE19899_A1 | Up | 0.4051773696 |
| GSE19899_A2 | Up | 0.5885949524 |
| PubMed_21979375_A1 | Up | 0.6351677217 |
| PubMed_21979375_A2 | Up | 0.6773844657 |
| GSE35957 | Down | -0.1094129518 |
| GSE36640 | Up | 0.4146348814 |
| GSE54402 | Up | 0.1262805037 |
| GSE9593 | Up | 0.1788034821 |
| GSE43922 | Up | 0.3976842431 |
| GSE24585 | Down | -0.6889157325 |
| GSE37065 | Down | -0.0925222338 |
| GSE28863_A1 | Down | -0.0729736727 |
| GSE28863_A2 | Up | 0.1556585547 |
| GSE28863_A3 | Up | 0.2156100157 |
| GSE28863_A4 | Down | -0.1539367561 |
| GSE48662 | Up | 0.1237383461 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-16-5p | MIMAT0000069 | MIRT032049 | Microarray | Functional MTI (Weak) | 21199864 |
| hsa-miR-16-5p | MIMAT0000069 | MIRT032049 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-532-3p | MIMAT0004780 | MIRT037920 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-423-5p | MIMAT0004748 | MIRT038131 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-92a-3p | MIMAT0000092 | MIRT049466 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
