HCSGD entry for KLF1

1. General information

Official gene symbolKLF1
Entrez ID10661
Gene full nameKruppel-like factor 1 (erythroid)
Other gene symbolsEKLF HBFQTL6 INLU
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000790Nuclear chromatinIDAcellular_component
GO:0000987Core promoter proximal region sequence-specific DNA bindingIDAmolecular_function
GO:0001701In utero embryonic developmentIEAbiological_process
GO:0001889Liver developmentIEAbiological_process
GO:0003700Sequence-specific DNA binding transcription factor activityTASmolecular_function
GO:0005634NucleusIDAcellular_component
GO:0006338Chromatin remodelingIEAbiological_process
GO:0006351Transcription, DNA-templatedIEAbiological_process
GO:0030218Erythrocyte differentiationIMPbiological_process
GO:0035162Embryonic hemopoiesisIEAbiological_process
GO:0043249Erythrocyte maturationIEAbiological_process
GO:0044212Transcription regulatory region DNA bindingIDAmolecular_function
GO:0045893Positive regulation of transcription, DNA-templatedIDAbiological_process
GO:0046872Metal ion bindingIEAmolecular_function
GO:1901653Cellular response to peptideIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.22046972380.91157303670.90191752291.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0057074165
GSE13712_SHEARUp0.0582864088
GSE13712_STATICDown-0.0442304795
GSE19018Up0.4434271019
GSE19899_A1Up0.1440105445
GSE19899_A2Up0.2250509656
PubMed_21979375_A1Up0.0416234617
PubMed_21979375_A2Down-0.0640762186
GSE35957Down-0.2323282223
GSE36640Up0.1360332506
GSE54402Up0.1250126169
GSE9593Down-0.0131222013
GSE43922Up0.1534545695
GSE24585Up0.0342364883
GSE37065Down-0.0839469626
GSE28863_A1Down-0.2004248282
GSE28863_A2Down-0.0448687765
GSE28863_A3Up0.4407239982
GSE28863_A4Up0.1044796801
GSE48662Up0.3792695975

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.