HCSGD entry for CES1
1. General information
| Official gene symbol | CES1 |
|---|---|
| Entrez ID | 1066 |
| Gene full name | carboxylesterase 1 |
| Other gene symbols | ACAT CE-1 CEH CES2 HMSE HMSE1 PCE-1 REH SES1 TGH hCE-1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005788 | Endoplasmic reticulum lumen | IEA | cellular_component |
| GO:0008152 | Metabolic process | TAS | biological_process |
| GO:0009636 | Response to toxic substance | TAS | biological_process |
| GO:0047374 | Methylumbelliferyl-acetate deacetylase activity | IEA | molecular_function |
| GO:0052689 | Carboxylic ester hydrolase activity | TAS | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0010189848 | 0.4054792523 | 0.0864207668 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.2413264292 |
| GSE13712_SHEAR | Down | -0.1682521660 |
| GSE13712_STATIC | Up | 0.1733921959 |
| GSE19018 | Down | -0.3003985223 |
| GSE19899_A1 | Up | 1.0755930423 |
| GSE19899_A2 | Up | 4.3711942432 |
| PubMed_21979375_A1 | Up | 7.3345954355 |
| PubMed_21979375_A2 | Up | 4.6828633150 |
| GSE35957 | Down | -1.2848302874 |
| GSE36640 | Up | 0.0278503375 |
| GSE54402 | Up | 2.6319035083 |
| GSE9593 | Down | -2.1741590767 |
| GSE43922 | Up | 1.2593530490 |
| GSE24585 | Down | -0.2069333941 |
| GSE37065 | Up | 0.1129344614 |
| GSE28863_A1 | - | - |
| GSE28863_A2 | - | - |
| GSE28863_A3 | - | - |
| GSE28863_A4 | - | - |
| GSE48662 | Up | 0.6608461109 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| L-Carnitine | DB00583 | APRD01070 |
| Probucol | DB01599 | - |
| Hydroxy-Phenyl-Acetic Acid 8-Methyl-8-Aza-Bicyclo[3.2.1]Oct-3-Yl Ester | DB02161 | EXPT01792 |
| Cholic Acid | DB02659 | EXPT00906 |
| 4-Piperidino-Piperidine | DB03056 | EXPT00227 |
| N-acetyl-alpha-neuraminic acid | DB03721 | EXPT02292 | EXPT02908 | EXPT02909 | DB01894 | DB02344 |
| N-Methylnaloxonium | DB04509 | EXPT02359 |
| Thenoyltrifluoroacetone | DB04795 | - |
| Cyclandelate | DB04838 | - |
| (1R)-1,2,2-TRIMETHYLPROPYL (R)-METHYLPHOSPHINATE | DB07821 | - |
| (1S,7S,8S,8AR)-1,2,3,7,8,8A-HEXAHYDRO-7-METHYL-8-[2-[(2R,4R)-TETRAHYDRO-4-HY DROXY-6-OXO-2H-PYRAN-2-YL]ETHYL]-1-NAPHTHALENOL | DB08224 | - |
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-197-3p | MIMAT0000227 | MIRT004206 | Microarray | Functional MTI (Weak) | 16822819 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
