HCSGD entry for PDPN

1. General information

Official gene symbolPDPN
Entrez ID10630
Gene full namepodoplanin
Other gene symbolsAGGRUS GP36 GP40 Gp38 HT1A-1 OTS8 PA2.26 T1A T1A-2
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000902Cell morphogenesisIEA ISSbiological_process
GO:0001726RuffleIEA ISScellular_component
GO:0001946LymphangiogenesisIEA ISSbiological_process
GO:0005372Water transmembrane transporter activityISSmolecular_function
GO:0005886Plasma membraneISScellular_component
GO:0005887Integral component of plasma membraneTAScellular_component
GO:0006693Prostaglandin metabolic processIEAbiological_process
GO:0006833Water transportISSbiological_process
GO:0006865Amino acid transportISSbiological_process
GO:0006928Cellular component movementIEAbiological_process
GO:0006954Inflammatory responseIEAbiological_process
GO:0007165Signal transductionIEAbiological_process
GO:0007399Nervous system developmentIEAbiological_process
GO:0008283Cell proliferationIEAbiological_process
GO:0008360Regulation of cell shapeIEAbiological_process
GO:0008517Folic acid transporter activityISSmolecular_function
GO:0009790Embryo developmentIEAbiological_process
GO:0009897External side of plasma membraneIEAcellular_component
GO:0010572Positive regulation of platelet activationIEAbiological_process
GO:0015171Amino acid transmembrane transporter activityISSmolecular_function
GO:0015250Water channel activityISSmolecular_function
GO:0015884Folic acid transportISSbiological_process
GO:0016021Integral component of membraneIEAcellular_component
GO:0016324Apical plasma membraneIEAcellular_component
GO:0016337Cell-cell adhesionIEAbiological_process
GO:0030027LamellipodiumIEA ISScellular_component
GO:0030175FilopodiumIEA ISScellular_component
GO:0030324Lung developmentISSbiological_process
GO:0030335Positive regulation of cell migrationIEAbiological_process
GO:0031258Lamellipodium membraneIEAcellular_component
GO:0031527Filopodium membraneIEAcellular_component
GO:0031528Microvillus membraneIEAcellular_component
GO:0032587Ruffle membraneIEAcellular_component
GO:0035239Tube morphogenesisIEAbiological_process
GO:0048286Lung alveolus developmentIEAbiological_process
GO:0051272Positive regulation of cellular component movementISSbiological_process
GO:0055093Response to hyperoxiaIEAbiological_process
GO:2000045Regulation of G1/S transition of mitotic cell cycleIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.00312535620.92286833330.15085054951.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0877787390
GSE13712_SHEARDown-0.0053137716
GSE13712_STATICUp0.0349264648
GSE19018Down-0.8800756008
GSE19899_A1Up0.4505277480
GSE19899_A2Up1.2332250540
PubMed_21979375_A1Up1.3334379925
PubMed_21979375_A2Up1.6346212988
GSE35957Up0.5256930430
GSE36640Down-0.0750335997
GSE54402Up0.4969882932
GSE9593Up0.0119644523
GSE43922Up0.7754856447
GSE24585Down-0.0917715374
GSE37065Up0.6297711104
GSE28863_A1Up0.6888375592
GSE28863_A2Up1.2072639882
GSE28863_A3Up0.4256031032
GSE28863_A4Up0.0172406972
GSE48662Down-0.1720694714

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-363-3pMIMAT0000707MIRT007320Luciferase reporter assayFunctional MTI23246488
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.