HCSGD entry for HEXIM1
1. General information
| Official gene symbol | HEXIM1 |
|---|---|
| Entrez ID | 10614 |
| Gene full name | hexamethylene bis-acetamide inducible 1 |
| Other gene symbols | CLP1 EDG1 HIS1 MAQ1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000122 | Negative regulation of transcription from RNA polymerase II promoter | IDA | biological_process |
| GO:0004861 | Cyclin-dependent protein serine/threonine kinase inhibitor activity | IDA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0006351 | Transcription, DNA-templated | IEA | biological_process |
| GO:0007507 | Heart development | IEA | biological_process |
| GO:0017069 | SnRNA binding | IDA | molecular_function |
| GO:0045736 | Negative regulation of cyclin-dependent protein serine/threonine kinase activity | IDA | biological_process |
| GO:0045892 | Negative regulation of transcription, DNA-templated | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0063556286 | 0.9297263706 | 0.2110220681 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.2634797127 |
| GSE13712_SHEAR | Up | 0.0191832044 |
| GSE13712_STATIC | Up | 0.1393059730 |
| GSE19018 | Down | -0.6908453491 |
| GSE19899_A1 | Up | 0.4310656648 |
| GSE19899_A2 | Up | 0.6592186802 |
| PubMed_21979375_A1 | Up | 0.2031504609 |
| PubMed_21979375_A2 | Up | 0.4654006151 |
| GSE35957 | Up | 0.7926307501 |
| GSE36640 | Up | 0.3230191154 |
| GSE54402 | Up | 0.0763553059 |
| GSE9593 | Down | -0.1453152987 |
| GSE43922 | Up | 0.3096379605 |
| GSE24585 | Up | 1.2572947429 |
| GSE37065 | Up | 0.3396223162 |
| GSE28863_A1 | Up | 0.4872051727 |
| GSE28863_A2 | Up | 0.4166411664 |
| GSE28863_A3 | Down | -0.0836071410 |
| GSE28863_A4 | Up | 0.3384925294 |
| GSE48662 | Up | 0.0362953874 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-503-5p | MIMAT0002874 | MIRT041122 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-324-3p | MIMAT0000762 | MIRT042951 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-222-3p | MIMAT0000279 | MIRT046764 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-20a-5p | MIMAT0000075 | MIRT050623 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-17-3p | MIMAT0000071 | MIRT050765 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-17-5p | MIMAT0000070 | MIRT051053 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
