HCSGD entry for SLCO1B1

1. General information

Official gene symbolSLCO1B1
Entrez ID10599
Gene full namesolute carrier organic anion transporter family, member 1B1
Other gene symbolsHBLRR LST-1 LST1 OATP-C OATP1B1 OATP2 OATPC SLC21A6
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005886Plasma membraneTAScellular_component
GO:0005887Integral component of plasma membraneTAScellular_component
GO:0008206Bile acid metabolic processTASbiological_process
GO:0015347Sodium-independent organic anion transmembrane transporter activityTASmolecular_function
GO:0015711Organic anion transportTASbiological_process
GO:0015721Bile acid and bile salt transportTASbiological_process
GO:0016020MembraneTAScellular_component
GO:0016323Basolateral plasma membraneIEAcellular_component
GO:0034220Ion transmembrane transportTASbiological_process
GO:0043252Sodium-independent organic anion transportTASbiological_process
GO:0044281Small molecule metabolic processTASbiological_process
GO:0055085Transmembrane transportTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.41589235590.94022947460.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0258748145
GSE13712_SHEARUp0.0576951385
GSE13712_STATICUp0.1145783140
GSE19018Up0.1836576579
GSE19899_A1Up0.0437747664
GSE19899_A2Up0.0513192721
PubMed_21979375_A1Up0.1376891815
PubMed_21979375_A2Down-0.2006177052
GSE35957Up0.0992081269
GSE36640Up0.0143354878
GSE54402Up0.0827910920
GSE9593Up0.1144964618
GSE43922Up0.0170177037
GSE24585Up0.1730070440
GSE37065Up0.1027049451
GSE28863_A1--
GSE28863_A2--
GSE28863_A3--
GSE28863_A4--
GSE48662Up0.0827065523

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

RifampicinDB01045 APRD00207 | EXPT02777
ClarithromycinDB01211 APRD00181

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-335-5pMIMAT0000765MIRT018741MicroarrayFunctional MTI (Weak)18185580
hsa-miR-26b-5pMIMAT0000083MIRT030029MicroarrayFunctional MTI (Weak)19088304
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.