HCSGD entry for IFITM2

1. General information

Official gene symbolIFITM2
Entrez ID10581
Gene full nameinterferon induced transmembrane protein 2
Other gene symbols1-8D DSPA2c
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005886Plasma membraneTAScellular_component
GO:0006955Immune responseTASbiological_process
GO:0009607Response to biotic stimulusIEAbiological_process
GO:0009615Response to virusIDAbiological_process
GO:0016021Integral component of membraneIEAcellular_component
GO:0019221Cytokine-mediated signaling pathwayTASbiological_process
GO:0034341Response to interferon-gammaIDAbiological_process
GO:0035455Response to interferon-alphaIDAbiological_process
GO:0035456Response to interferon-betaIDAbiological_process
GO:0045071Negative regulation of viral genome replicationIDAbiological_process
GO:0046597Negative regulation of viral entry into host cellIDAbiological_process
GO:0051607Defense response to virusIEAbiological_process
GO:0060337Type I interferon signaling pathwayTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.54240003800.01669292960.99999024730.2525141379

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.2037618328
GSE13712_SHEARUp0.2264630631
GSE13712_STATICUp0.4924073263
GSE19018Down-0.7078406539
GSE19899_A1Down-0.7554087620
GSE19899_A2Down-1.0074861216
PubMed_21979375_A1Up0.2125167957
PubMed_21979375_A2Down-0.5402599576
GSE35957Down-0.4256681960
GSE36640Up0.5320195035
GSE54402Down-1.3838362020
GSE9593Down-0.0674076509
GSE43922Down-0.5991979940
GSE24585Up0.7623395588
GSE37065Up0.0884855910
GSE28863_A1Down-0.1227839996
GSE28863_A2Down-0.3863259208
GSE28863_A3Up0.1231844629
GSE28863_A4Up0.0410782721
GSE48662Up0.1382049239

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.