HCSGD entry for SLU7
1. General information
| Official gene symbol | SLU7 |
|---|---|
| Entrez ID | 10569 |
| Gene full name | SLU7 splicing factor homolog (S. cerevisiae) |
| Other gene symbols | 9G8 hSlu7 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000375 | RNA splicing, via transesterification reactions | IDA | biological_process |
| GO:0000380 | Alternative mRNA splicing, via spliceosome | IDA | biological_process |
| GO:0000386 | Second spliceosomal transesterification activity | IDA | molecular_function |
| GO:0000389 | MRNA 3'-splice site recognition | IDA | biological_process |
| GO:0000398 | MRNA splicing, via spliceosome | IC | biological_process |
| GO:0003676 | Nucleic acid binding | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005681 | Spliceosomal complex | IDA | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0006886 | Intracellular protein transport | IDA | biological_process |
| GO:0008270 | Zinc ion binding | IDA IEA | molecular_function |
| GO:0016607 | Nuclear speck | IDA | cellular_component |
| GO:0030532 | Small nuclear ribonucleoprotein complex | IDA | cellular_component |
| GO:0030628 | Pre-mRNA 3'-splice site binding | IDA | molecular_function |
| GO:0034605 | Cellular response to heat | IDA | biological_process |
| GO:0043231 | Intracellular membrane-bounded organelle | IDA | cellular_component |
| GO:0071013 | Catalytic step 2 spliceosome | IDA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0471666312 | 0.9525723149 | 0.4804461687 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.5394015080 |
| GSE13712_SHEAR | Up | 0.1595465224 |
| GSE13712_STATIC | Down | -0.0568008168 |
| GSE19018 | Up | 0.2680347625 |
| GSE19899_A1 | Up | 0.5629377333 |
| GSE19899_A2 | Up | 0.5484896227 |
| PubMed_21979375_A1 | Up | 0.9457206108 |
| PubMed_21979375_A2 | Up | 0.2947078473 |
| GSE35957 | Up | 0.0635510015 |
| GSE36640 | Up | 0.2486331972 |
| GSE54402 | Up | 0.1238181719 |
| GSE9593 | Up | 0.0199288662 |
| GSE43922 | Up | 0.0950829047 |
| GSE24585 | Up | 0.2063762356 |
| GSE37065 | Up | 0.2167734397 |
| GSE28863_A1 | Down | -0.0268938224 |
| GSE28863_A2 | Up | 0.1863335505 |
| GSE28863_A3 | Down | -0.3376150179 |
| GSE28863_A4 | Down | -0.2516607256 |
| GSE48662 | Down | -0.2253550334 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-124-3p | MIMAT0000422 | MIRT023059 | Proteomics;Microarray | Functional MTI (Weak) | 18668037 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
