HCSGD entry for SLC19A2
1. General information
| Official gene symbol | SLC19A2 |
|---|---|
| Entrez ID | 10560 |
| Gene full name | solute carrier family 19 (thiamine transporter), member 2 |
| Other gene symbols | TC1 THMD1 THT1 THTR1 TRMA |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005886 | Plasma membrane | TAS | cellular_component |
| GO:0006766 | Vitamin metabolic process | TAS | biological_process |
| GO:0006767 | Water-soluble vitamin metabolic process | TAS | biological_process |
| GO:0006810 | Transport | IEA | biological_process |
| GO:0006855 | Drug transmembrane transport | ISS TAS | biological_process |
| GO:0008517 | Folic acid transporter activity | NAS | molecular_function |
| GO:0015234 | Thiamine transmembrane transporter activity | TAS | molecular_function |
| GO:0015403 | Thiamine uptake transmembrane transporter activity | ISS | molecular_function |
| GO:0015884 | Folic acid transport | NAS | biological_process |
| GO:0015888 | Thiamine transport | NAS | biological_process |
| GO:0016021 | Integral component of membrane | IEA NAS | cellular_component |
| GO:0035461 | Vitamin transmembrane transport | ISS TAS | biological_process |
| GO:0042723 | Thiamine-containing compound metabolic process | TAS | biological_process |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:0051181 | Cofactor transport | NAS | biological_process |
| GO:0055085 | Transmembrane transport | ISS TAS | biological_process |
| GO:0071934 | Thiamine transmembrane transport | ISS TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0007483264 | 0.1843873257 | 0.0773316602 | 0.8327415337 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -1.6413632588 |
| GSE13712_SHEAR | Up | 0.8075343152 |
| GSE13712_STATIC | Up | 0.9240710490 |
| GSE19018 | Down | -1.0677676298 |
| GSE19899_A1 | Up | 1.6761083268 |
| GSE19899_A2 | Up | 2.2276174400 |
| PubMed_21979375_A1 | Up | 2.5482275625 |
| PubMed_21979375_A2 | Up | 2.6034936565 |
| GSE35957 | Up | 0.9402665185 |
| GSE36640 | Up | 0.4849177687 |
| GSE54402 | Up | 0.7711701318 |
| GSE9593 | Up | 0.5493081180 |
| GSE43922 | Up | 1.4231142245 |
| GSE24585 | Up | 0.2050864244 |
| GSE37065 | Up | 0.5669252587 |
| GSE28863_A1 | Down | -0.5859396187 |
| GSE28863_A2 | Up | 0.2801352356 |
| GSE28863_A3 | Down | -0.5965816012 |
| GSE28863_A4 | Down | -0.4961350345 |
| GSE48662 | Down | -0.2960317679 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| Thiamine | DB00152 | NUTR00009 | APRD00552 | EXPT03222 |
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-122-5p | MIMAT0000421 | MIRT023284 | Microarray | Functional MTI (Weak) | 17612493 |
| hsa-miR-215-5p | MIMAT0000272 | MIRT024357 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-192-5p | MIMAT0000222 | MIRT026524 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-98-5p | MIMAT0000096 | MIRT027662 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-miR-26b-5p | MIMAT0000083 | MIRT029562 | Sequencing | Functional MTI (Weak) | 20371350 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
