HCSGD entry for AGPAT2


1. General information

Official gene symbolAGPAT2
Entrez ID10555
Gene full name1-acylglycerol-3-phosphate O-acyltransferase 2
Other gene symbols1-AGPAT2 BSCL BSCL1 LPAAB LPAAT-beta
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001819Positive regulation of cytokine productionIMPbiological_process
GO:0001961Positive regulation of cytokine-mediated signaling pathwayICbiological_process
GO:00038411-acylglycerol-3-phosphate O-acyltransferase activityIGI NASmolecular_function
GO:0005783Endoplasmic reticulumISScellular_component
GO:0005789Endoplasmic reticulum membraneTAScellular_component
GO:0006644Phospholipid metabolic processNAS TASbiological_process
GO:0006654Phosphatidic acid biosynthetic processIGI TASbiological_process
GO:0008544Epidermis developmentIEAbiological_process
GO:0016021Integral component of membraneIEAcellular_component
GO:0016024CDP-diacylglycerol biosynthetic processIEAbiological_process
GO:0019432Triglyceride biosynthetic processTASbiological_process
GO:0044255Cellular lipid metabolic processTASbiological_process
GO:0044281Small molecule metabolic processTASbiological_process
GO:0046474Glycerophospholipid biosynthetic processTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.18899941870.61321334680.84697383381.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.1718345934
GSE13712_SHEARDown-0.5673203452
GSE13712_STATICDown-0.5182910825
GSE19018Up0.1303379843
GSE19899_A1Up0.1170108932
GSE19899_A2Up0.6831192176
PubMed_21979375_A1Up0.6518672483
PubMed_21979375_A2Up0.5250576146
GSE35957Up0.0521999842
GSE36640Up0.1604971390
GSE54402Up0.0484360125
GSE9593Up0.0992786357
GSE43922Up0.2951098749
GSE24585Down-0.2491844163
GSE37065Down-0.1007910428
GSE28863_A1Down-0.2512881833
GSE28863_A2Down-0.3039268927
GSE28863_A3Up0.2261503844
GSE28863_A4Up0.0559901914
GSE48662Up0.2780177015

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-744-5pMIMAT0004945MIRT037533CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.