HCSGD entry for PROCR
1. General information
| Official gene symbol | PROCR |
|---|---|
| Entrez ID | 10544 |
| Gene full name | protein C receptor, endothelial |
| Other gene symbols | CCCA CCD41 CD201 EPCR |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004872 | Receptor activity | TAS | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005813 | Centrosome | IEA | cellular_component |
| GO:0005887 | Integral component of plasma membrane | TAS | cellular_component |
| GO:0006955 | Immune response | IEA | biological_process |
| GO:0007596 | Blood coagulation | IEA | biological_process |
| GO:0019882 | Antigen processing and presentation | IEA | biological_process |
| GO:0050819 | Negative regulation of coagulation | IMP | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0023351696 | 0.9577099996 | 0.1288553459 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.2697979366 |
| GSE13712_SHEAR | Down | -0.0784614562 |
| GSE13712_STATIC | Up | 0.3897369438 |
| GSE19018 | Up | 0.0096051078 |
| GSE19899_A1 | Up | 1.3762170222 |
| GSE19899_A2 | Up | 0.8671089802 |
| PubMed_21979375_A1 | Up | 0.4684517754 |
| PubMed_21979375_A2 | Up | 1.1975061848 |
| GSE35957 | Down | -0.0202559197 |
| GSE36640 | Up | 0.7762741991 |
| GSE54402 | Up | 0.3764695332 |
| GSE9593 | Down | -0.3551708564 |
| GSE43922 | Up | 1.3669725661 |
| GSE24585 | Down | -0.3237114957 |
| GSE37065 | Up | 0.8854512713 |
| GSE28863_A1 | Up | 0.6542505694 |
| GSE28863_A2 | Up | 0.2258941766 |
| GSE28863_A3 | Down | -0.1549009762 |
| GSE28863_A4 | Up | 0.4497330272 |
| GSE48662 | Down | -0.2620327062 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| Phosphatidylethanolamine | DB04327 | EXPT02690 |
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-375 | MIMAT0000728 | MIRT019919 | Microarray | Functional MTI (Weak) | 20215506 |
| hsa-miR-1 | MIMAT0000416 | MIRT023818 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-877-3p | MIMAT0004950 | MIRT037191 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
