HCSGD entry for LEPREL2
1. General information
| Official gene symbol | LEPREL2 |
|---|---|
| Entrez ID | 10536 |
| Gene full name | leprecan-like 2 |
| Other gene symbols | GRCB HSU47926 P3H3 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005506 | Iron ion binding | IEA | molecular_function |
| GO:0005788 | Endoplasmic reticulum lumen | TAS | cellular_component |
| GO:0008285 | Negative regulation of cell proliferation | IDA | biological_process |
| GO:0016706 | Oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors | IEA | molecular_function |
| GO:0019797 | Procollagen-proline 3-dioxygenase activity | IEA | molecular_function |
| GO:0030198 | Extracellular matrix organization | TAS | biological_process |
| GO:0031418 | L-ascorbic acid binding | IEA | molecular_function |
Entries Per Page
Displaying Page of
4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9945060598 | 0.0054730443 | 0.9999902473 | 0.1495908619 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1614495813 |
| GSE13712_SHEAR | Down | -0.5502258721 |
| GSE13712_STATIC | Down | -0.2737779866 |
| GSE19018 | Up | 0.0295890321 |
| GSE19899_A1 | Down | -0.6102968467 |
| GSE19899_A2 | Down | -1.3122511569 |
| PubMed_21979375_A1 | Down | -0.8494206568 |
| PubMed_21979375_A2 | Down | -1.0975039374 |
| GSE35957 | Down | -0.4139183725 |
| GSE36640 | Down | -0.1208271011 |
| GSE54402 | Down | -0.9658161781 |
| GSE9593 | Up | 0.0247579203 |
| GSE43922 | Down | -0.1857860195 |
| GSE24585 | Down | -0.3525430508 |
| GSE37065 | Down | -0.0571725247 |
| GSE28863_A1 | - | - |
| GSE28863_A2 | - | - |
| GSE28863_A3 | - | - |
| GSE28863_A4 | - | - |
| GSE48662 | Down | -0.0070707776 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| Vitamin C | DB00126 | NUTR00001 | APRD00084 | EXPT00568 | DB09541 |
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT017171 | Microarray | Functional MTI (Weak) | 18185580 |
| hsa-miR-155-5p | MIMAT0000646 | MIRT020590 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-1 | MIMAT0000416 | MIRT023571 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-331-3p | MIMAT0000760 | MIRT043480 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-149-5p | MIMAT0000450 | MIRT045511 | CLASH | Functional MTI (Weak) | 23622248 |
Entries Per Page
Displaying Page of
- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
