HCSGD entry for DEAF1
1. General information
| Official gene symbol | DEAF1 |
|---|---|
| Entrez ID | 10522 |
| Gene full name | DEAF1 transcription factor |
| Other gene symbols | NUDR SPN ZMYND5 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001843 | Neural tube closure | ISS | biological_process |
| GO:0003677 | DNA binding | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005576 | Extracellular region | IEA | cellular_component |
| GO:0005634 | Nucleus | IDA IEA | cellular_component |
| GO:0005667 | Transcription factor complex | IEA | cellular_component |
| GO:0005737 | Cytoplasm | IDA IEA | cellular_component |
| GO:0006357 | Regulation of transcription from RNA polymerase II promoter | IEA | biological_process |
| GO:0006366 | Transcription from RNA polymerase II promoter | IEA | biological_process |
| GO:0007281 | Germ cell development | TAS | biological_process |
| GO:0009653 | Anatomical structure morphogenesis | TAS | biological_process |
| GO:0033599 | Regulation of mammary gland epithelial cell proliferation | IDA | biological_process |
| GO:0046872 | Metal ion binding | IEA | molecular_function |
| GO:0048706 | Embryonic skeletal system development | ISS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.1145386725 | 0.8794606854 | 0.6957702285 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0371215050 |
| GSE13712_SHEAR | Down | -0.2751798814 |
| GSE13712_STATIC | Down | -0.3703891583 |
| GSE19018 | Up | 0.1390662919 |
| GSE19899_A1 | Down | -0.0380989562 |
| GSE19899_A2 | Up | 0.1580097869 |
| PubMed_21979375_A1 | Down | -0.0788378351 |
| PubMed_21979375_A2 | Up | 0.2505513662 |
| GSE35957 | Up | 0.0470569076 |
| GSE36640 | Up | 0.1087179163 |
| GSE54402 | Up | 0.0495904717 |
| GSE9593 | Up | 0.4228940404 |
| GSE43922 | Up | 0.0462038993 |
| GSE24585 | Up | 0.0251791151 |
| GSE37065 | Down | -0.1307821409 |
| GSE28863_A1 | Up | 0.8653119126 |
| GSE28863_A2 | Up | 0.5944659185 |
| GSE28863_A3 | Down | -0.1408092978 |
| GSE28863_A4 | Up | 0.0199975570 |
| GSE48662 | Up | 0.5359935338 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-215-5p | MIMAT0000272 | MIRT024571 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-192-5p | MIMAT0000222 | MIRT026170 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-324-5p | MIMAT0000761 | MIRT043165 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-100-5p | MIMAT0000098 | MIRT048528 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-25-3p | MIMAT0000081 | MIRT050256 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
