HCSGD entry for SEMA4B


1. General information

Official gene symbolSEMA4B
Entrez ID10509
Gene full namesema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B
Other gene symbolsSEMAC SemC
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004872Receptor activityIEAmolecular_function
GO:0007275Multicellular organismal developmentIEAbiological_process
GO:0007399Nervous system developmentIEAbiological_process
GO:0016020MembraneIEAcellular_component
GO:0016021Integral component of membraneIEAcellular_component
GO:0030154Cell differentiationIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.03648357970.76030647390.43328291251.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.1413187761
GSE13712_SHEARUp0.0677588700
GSE13712_STATICUp0.6623823542
GSE19018Up0.1314630677
GSE19899_A1Up0.2304317405
GSE19899_A2Up0.3401553188
PubMed_21979375_A1Up0.4558881469
PubMed_21979375_A2Up0.8550339424
GSE35957Down-1.2957602734
GSE36640Down-1.9194756096
GSE54402Up0.5430679123
GSE9593Down-0.1299063762
GSE43922Up0.4299354725
GSE24585Up0.2529037608
GSE37065Up0.3089008867
GSE28863_A1Down-0.0131212571
GSE28863_A2Up0.4235676546
GSE28863_A3Up0.0660255593
GSE28863_A4Up0.1472138910
GSE48662Down-0.0785524336

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-335-5pMIMAT0000765MIRT017490MicroarrayFunctional MTI (Weak)18185580
hsa-let-7e-5pMIMAT0000066MIRT051498CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.