HCSGD entry for SEMA6B


1. General information

Official gene symbolSEMA6B
Entrez ID10501
Gene full namesema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B
Other gene symbolsSEM-SEMA-Y SEMA-VIB SEMAN semaZ
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004872Receptor activityIEAmolecular_function
GO:0005886Plasma membraneIEAcellular_component
GO:0007399Nervous system developmentIEAbiological_process
GO:0016021Integral component of membraneIEAcellular_component
GO:0030154Cell differentiationIEAbiological_process
GO:0030215Semaphorin receptor bindingIEAmolecular_function
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.28807707910.86509858670.98678430911.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0810643695
GSE13712_SHEARUp0.6589534128
GSE13712_STATICUp0.3529007601
GSE19018Up0.0857333336
GSE19899_A1Down-0.0279100730
GSE19899_A2Up0.2110496763
PubMed_21979375_A1Down-0.0751149738
PubMed_21979375_A2Down-0.1619396660
GSE35957Up0.1815121584
GSE36640Up0.1118739182
GSE54402Up0.0392123213
GSE9593Down-0.0420328962
GSE43922Up0.0692105224
GSE24585Up0.1708167854
GSE37065Down-0.1026593196
GSE28863_A1Down-0.0553966305
GSE28863_A2Down-0.1804587595
GSE28863_A3Up0.3523188777
GSE28863_A4Up0.0499315553
GSE48662Up0.1517628072

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-19b-3pMIMAT0000074MIRT031258SequencingFunctional MTI (Weak)20371350
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.