HCSGD entry for ENOX2
1. General information
| Official gene symbol | ENOX2 |
|---|---|
| Entrez ID | 10495 |
| Gene full name | ecto-NOX disulfide-thiol exchanger 2 |
| Other gene symbols | APK1 COVA1 tNOX |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000166 | Nucleotide binding | IEA | molecular_function |
| GO:0003676 | Nucleic acid binding | IEA | molecular_function |
| GO:0005615 | Extracellular space | IEA | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0007624 | Ultradian rhythm | IDA | biological_process |
| GO:0009897 | External side of plasma membrane | IDA | cellular_component |
| GO:0015035 | Protein disulfide oxidoreductase activity | IDA | molecular_function |
| GO:0016049 | Cell growth | NAS | biological_process |
| GO:0040008 | Regulation of growth | IEA | biological_process |
| GO:0055114 | Oxidation-reduction process | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.7289944265 | 0.6971575890 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0339055262 |
| GSE13712_SHEAR | Down | -0.1647321309 |
| GSE13712_STATIC | Up | 0.0046346253 |
| GSE19018 | Down | -0.0287924618 |
| GSE19899_A1 | Down | -0.0115276100 |
| GSE19899_A2 | Down | -0.0401273925 |
| PubMed_21979375_A1 | Up | 0.1402499250 |
| PubMed_21979375_A2 | Down | -0.1230382185 |
| GSE35957 | Up | 0.0609886665 |
| GSE36640 | Down | -0.2471054183 |
| GSE54402 | Up | 0.1499084222 |
| GSE9593 | Up | 0.0667444964 |
| GSE43922 | Down | -0.0155042604 |
| GSE24585 | Up | 0.0644635685 |
| GSE37065 | Up | 0.0295465859 |
| GSE28863_A1 | Up | 0.5530276872 |
| GSE28863_A2 | Up | 0.0953688538 |
| GSE28863_A3 | Down | -0.1226497331 |
| GSE28863_A4 | Down | -0.0480429226 |
| GSE48662 | Down | -0.0919605246 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| Phenoxodiol | DB04915 | - |
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-193b-3p | MIMAT0002819 | MIRT016542 | Microarray | Functional MTI (Weak) | 20304954 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
