HCSGD entry for GPNMB
1. General information
| Official gene symbol | GPNMB |
|---|---|
| Entrez ID | 10457 |
| Gene full name | glycoprotein (transmembrane) nmb |
| Other gene symbols | HGFIN NMB |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001649 | Osteoblast differentiation | IEA | biological_process |
| GO:0005178 | Integrin binding | IEA | molecular_function |
| GO:0005887 | Integral component of plasma membrane | IEA | cellular_component |
| GO:0007155 | Cell adhesion | IEA | biological_process |
| GO:0008201 | Heparin binding | IEA | molecular_function |
| GO:0008285 | Negative regulation of cell proliferation | TAS | biological_process |
| GO:0016021 | Integral component of membrane | IEA TAS | cellular_component |
| GO:0030282 | Bone mineralization | IEA | biological_process |
| GO:0042470 | Melanosome | IEA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0000326583 | 0.9951855401 | 0.0159185185 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 1.7887565996 |
| GSE13712_SHEAR | Up | 1.0183833446 |
| GSE13712_STATIC | Up | 1.8831585518 |
| GSE19018 | Down | -0.1875476279 |
| GSE19899_A1 | Up | 0.2325074931 |
| GSE19899_A2 | Up | 0.9244727262 |
| PubMed_21979375_A1 | Up | 0.5797624666 |
| PubMed_21979375_A2 | Up | 2.3061218374 |
| GSE35957 | Up | 0.8529559317 |
| GSE36640 | Up | 0.5935457700 |
| GSE54402 | Up | 2.1922572660 |
| GSE9593 | Up | 3.5812410223 |
| GSE43922 | Up | 1.2328020355 |
| GSE24585 | Up | 0.4627084973 |
| GSE37065 | Up | 0.7284979606 |
| GSE28863_A1 | Up | 0.1023870967 |
| GSE28863_A2 | Up | 1.8127676224 |
| GSE28863_A3 | Up | 0.0687932898 |
| GSE28863_A4 | Down | -0.3141822654 |
| GSE48662 | Down | -0.0090132782 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-26b-5p | MIMAT0000083 | MIRT030247 | Microarray | Functional MTI (Weak) | 19088304 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
