HCSGD entry for ZER1
1. General information
| Official gene symbol | ZER1 |
|---|---|
| Entrez ID | 10444 |
| Gene full name | zyg-11 related, cell cycle regulator |
| Other gene symbols | C9orf60 ZYG ZYG11BL |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004842 | Ubiquitin-protein ligase activity | IMP | molecular_function |
| GO:0008152 | Metabolic process | IMP | biological_process |
| GO:0016567 | Protein ubiquitination | IMP | biological_process |
| GO:0031462 | Cul2-RING ubiquitin ligase complex | IDA | cellular_component |
| GO:0051438 | Regulation of ubiquitin-protein ligase activity | IMP | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.1901382470 | 0.8016955359 | 0.8479296227 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0958563519 |
| GSE13712_SHEAR | Down | -0.1218805058 |
| GSE13712_STATIC | Down | -0.0784406826 |
| GSE19018 | Up | 0.2743870339 |
| GSE19899_A1 | Up | 0.0442203320 |
| GSE19899_A2 | Up | 0.2945699228 |
| PubMed_21979375_A1 | Up | 0.0375717142 |
| PubMed_21979375_A2 | Up | 0.2530336150 |
| GSE35957 | Up | 0.1257144080 |
| GSE36640 | Up | 0.4329697502 |
| GSE54402 | Down | -0.0241821195 |
| GSE9593 | Up | 0.1771201637 |
| GSE43922 | Up | 0.0298772725 |
| GSE24585 | Up | 0.4499685593 |
| GSE37065 | Down | -0.0944173387 |
| GSE28863_A1 | Up | 0.2514467044 |
| GSE28863_A2 | Up | 0.2901732896 |
| GSE28863_A3 | Down | -0.4431485815 |
| GSE28863_A4 | Down | -0.4105398858 |
| GSE48662 | Up | 0.3318988338 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT017191 | Microarray | Functional MTI (Weak) | 18185580 |
| hsa-miR-19b-3p | MIMAT0000074 | MIRT031202 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-615-3p | MIMAT0003283 | MIRT040068 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-331-3p | MIMAT0000760 | MIRT043566 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7b-5p | MIMAT0000063 | MIRT052074 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
