HCSGD entry for CDC42EP2

1. General information

Official gene symbolCDC42EP2
Entrez ID10435
Gene full nameCDC42 effector protein (Rho GTPase binding) 2
Other gene symbolsBORG1 CEP2
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001515Opioid peptide activityIEAmolecular_function
GO:0005100Rho GTPase activator activityIMPmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005737CytoplasmIDAcellular_component
GO:0005886Plasma membraneIDAcellular_component
GO:0007015Actin filament organizationNASbiological_process
GO:0008360Regulation of cell shapeIDAbiological_process
GO:0012505Endomembrane systemIEAcellular_component
GO:0015630Microtubule cytoskeletonIDAcellular_component
GO:0016020MembraneIDAcellular_component
GO:0017049GTP-Rho bindingIPImolecular_function
GO:0030036Actin cytoskeleton organizationIDAbiological_process
GO:0030838Positive regulation of actin filament polymerizationIDAbiological_process
GO:0031274Positive regulation of pseudopodium assemblyIDAbiological_process
GO:0031334Positive regulation of protein complex assemblyTASbiological_process
GO:0032320Positive regulation of Ras GTPase activityIMPbiological_process
GO:0032321Positive regulation of Rho GTPase activityIMPbiological_process
GO:0043085Positive regulation of catalytic activityIMPbiological_process
GO:0043547Positive regulation of GTPase activityIMPbiological_process
GO:0050790Regulation of catalytic activityIMPbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.00350868510.98481253750.16091306621.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.1240264610
GSE13712_SHEARUp0.9071046491
GSE13712_STATICUp0.3827846529
GSE19018Up0.1748058776
GSE19899_A1Down-0.0504316598
GSE19899_A2Up2.0789799353
PubMed_21979375_A1Up2.0561300605
PubMed_21979375_A2Up1.9076448546
GSE35957Up0.7682147840
GSE36640Down-0.0029526442
GSE54402Up0.4087336632
GSE9593Up0.3956274137
GSE43922Up0.3208321824
GSE24585Up0.0993181440
GSE37065Down-0.2551530537
GSE28863_A1Up0.2556858129
GSE28863_A2Up0.2782866747
GSE28863_A3Up0.2857559568
GSE28863_A4Up0.0546908210
GSE48662Down-0.6650702834

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.