HCSGD entry for PGRMC2
1. General information
| Official gene symbol | PGRMC2 |
|---|---|
| Entrez ID | 10424 |
| Gene full name | progesterone receptor membrane component 2 |
| Other gene symbols | DG6 PMBP |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003707 | Steroid hormone receptor activity | TAS | molecular_function |
| GO:0005496 | Steroid binding | IEA | molecular_function |
| GO:0007165 | Signal transduction | TAS | biological_process |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0020037 | Heme binding | IEA | molecular_function |
| GO:0043401 | Steroid hormone mediated signaling pathway | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.4277235211 | 0.0852241974 | 0.9999902473 | 0.5542134535 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.7998031433 |
| GSE13712_SHEAR | Down | -0.0151753783 |
| GSE13712_STATIC | Up | 0.4405350822 |
| GSE19018 | Up | 0.0803901439 |
| GSE19899_A1 | Down | -0.1875411874 |
| GSE19899_A2 | Down | -0.1728487799 |
| PubMed_21979375_A1 | Down | -0.1903257998 |
| PubMed_21979375_A2 | Down | -0.0820638049 |
| GSE35957 | Up | 1.4834436501 |
| GSE36640 | Up | 0.7032939426 |
| GSE54402 | Down | -1.0455538362 |
| GSE9593 | Up | 0.5977250085 |
| GSE43922 | Down | -0.0068242620 |
| GSE24585 | Down | -0.1876655460 |
| GSE37065 | Down | -0.1512819021 |
| GSE28863_A1 | Down | -0.2519406901 |
| GSE28863_A2 | Up | 0.4325677281 |
| GSE28863_A3 | Up | 0.0579719134 |
| GSE28863_A4 | Down | -0.2476743348 |
| GSE48662 | Down | -0.2774429874 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-124-3p | MIMAT0000422 | MIRT002672 | Microarray | Functional MTI (Weak) | 15685193 |
| hsa-miR-124-3p | MIMAT0000422 | MIRT002672 | Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-155-5p | MIMAT0000646 | MIRT020691 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-1 | MIMAT0000416 | MIRT023684 | Proteomics;Microarray | Non-Functional MTI (Weak) | 18668037 |
| hsa-miR-21-5p | MIMAT0000076 | MIRT030788 | Microarray | Functional MTI (Weak) | 18591254 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
