HCSGD entry for TESK2
1. General information
| Official gene symbol | TESK2 |
|---|---|
| Entrez ID | 10420 |
| Gene full name | testis-specific kinase 2 |
| Other gene symbols | |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004672 | Protein kinase activity | IEA TAS | molecular_function |
| GO:0004674 | Protein serine/threonine kinase activity | IEA ISS | molecular_function |
| GO:0004712 | Protein serine/threonine/tyrosine kinase activity | IEA | molecular_function |
| GO:0004713 | Protein tyrosine kinase activity | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005634 | Nucleus | IDA ISS | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IEA | cellular_component |
| GO:0006468 | Protein phosphorylation | ISS | biological_process |
| GO:0007283 | Spermatogenesis | IEA ISS | biological_process |
| GO:0030036 | Actin cytoskeleton organization | IEA ISS | biological_process |
| GO:0046872 | Metal ion binding | IEA | molecular_function |
| GO:0048041 | Focal adhesion assembly | IEA ISS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.5258001976 | 0.2634747692 | 0.9999902473 | 0.9853759091 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1335080289 |
| GSE13712_SHEAR | Down | -0.3112739042 |
| GSE13712_STATIC | Down | -0.4320089257 |
| GSE19018 | Up | 0.2828415638 |
| GSE19899_A1 | Down | -0.0255840183 |
| GSE19899_A2 | Down | -0.2933704238 |
| PubMed_21979375_A1 | Up | 0.0500926289 |
| PubMed_21979375_A2 | Down | -0.1344579603 |
| GSE35957 | Down | -0.1955736875 |
| GSE36640 | Up | 0.0336129190 |
| GSE54402 | Up | 0.1057472733 |
| GSE9593 | Down | -0.0709308622 |
| GSE43922 | Up | 0.0273350961 |
| GSE24585 | Up | 0.7516237116 |
| GSE37065 | Up | 0.1550077617 |
| GSE28863_A1 | Down | -0.4106923113 |
| GSE28863_A2 | Down | -0.1375803136 |
| GSE28863_A3 | Down | -0.1111644393 |
| GSE28863_A4 | Down | -0.0456715799 |
| GSE48662 | Up | 0.4349040804 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-9-5p | MIMAT0000441 | MIRT021469 | Microarray | Functional MTI (Weak) | 17612493 |
| hsa-miR-21-5p | MIMAT0000076 | MIRT031008 | Microarray | Functional MTI (Weak) | 18591254 |
| hsa-miR-93-3p | MIMAT0004509 | MIRT038778 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
