HCSGD entry for PRG3
1. General information
| Official gene symbol | PRG3 |
|---|---|
| Entrez ID | 10394 |
| Gene full name | proteoglycan 3 |
| Other gene symbols | MBP2 MBPH |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001694 | Histamine biosynthetic process | IDA | biological_process |
| GO:0006955 | Immune response | IEA | biological_process |
| GO:0017148 | Negative regulation of translation | IDA | biological_process |
| GO:0019370 | Leukotriene biosynthetic process | IDA | biological_process |
| GO:0030246 | Carbohydrate binding | IEA | molecular_function |
| GO:0042119 | Neutrophil activation | IDA | biological_process |
| GO:0042554 | Superoxide anion generation | IDA | biological_process |
| GO:0045416 | Positive regulation of interleukin-8 biosynthetic process | IDA | biological_process |
| GO:0045575 | Basophil activation | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.7668376999 | 0.6798241176 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1046296907 |
| GSE13712_SHEAR | Down | -0.0751114688 |
| GSE13712_STATIC | Down | -0.0012398832 |
| GSE19018 | Up | 0.0083452290 |
| GSE19899_A1 | Up | 0.0632626622 |
| GSE19899_A2 | Up | 0.3060716668 |
| PubMed_21979375_A1 | Down | -0.1778028244 |
| PubMed_21979375_A2 | Down | -0.2075413430 |
| GSE35957 | Up | 0.0210159085 |
| GSE36640 | Up | 0.0130787510 |
| GSE54402 | Down | -0.0656667100 |
| GSE9593 | Up | 0.0786954523 |
| GSE43922 | Up | 0.0346079430 |
| GSE24585 | Down | -0.0176129501 |
| GSE37065 | Up | 0.1128250403 |
| GSE28863_A1 | Down | -0.0309056194 |
| GSE28863_A2 | Down | -0.2913819720 |
| GSE28863_A3 | Up | 0.2826360501 |
| GSE28863_A4 | Up | 0.1650603825 |
| GSE48662 | Down | -0.0871257729 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT017446 | Microarray | Functional MTI (Weak) | 18185580 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
