HCSGD entry for ANAPC10

1. General information

Official gene symbolANAPC10
Entrez ID10393
Gene full nameanaphase promoting complex subunit 10
Other gene symbolsAPC10 DOC1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000086G2/M transition of mitotic cell cycleTASbiological_process
GO:0000090Mitotic anaphaseTASbiological_process
GO:0000278Mitotic cell cycleTASbiological_process
GO:0004842Ubiquitin-protein ligase activityTASmolecular_function
GO:0005654NucleoplasmTAScellular_component
GO:0005680Anaphase-promoting complexIDA NAScellular_component
GO:0005737CytoplasmIEAcellular_component
GO:0005829CytosolTAScellular_component
GO:0006511Ubiquitin-dependent protein catabolic processTASbiological_process
GO:0007067MitosisNASbiological_process
GO:0007094Mitotic spindle assembly checkpointTASbiological_process
GO:0031145Anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic processTASbiological_process
GO:0051436Negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycleTASbiological_process
GO:0051437Positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycleTASbiological_process
GO:0051439Regulation of ubiquitin-protein ligase activity involved in mitotic cell cycleTASbiological_process
GO:0070979Protein K11-linked ubiquitinationIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.17081907600.91825746360.81306470801.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.1751669811
GSE13712_SHEARDown-0.1872058497
GSE13712_STATICUp0.4259986941
GSE19018Down-0.0501169654
GSE19899_A1Down-0.1478998850
GSE19899_A2Up0.4050890920
PubMed_21979375_A1Up0.8866992473
PubMed_21979375_A2Up0.1495012502
GSE35957Up0.0481755775
GSE36640Up0.5270647860
GSE54402Up0.0518383086
GSE9593Down-0.1461811655
GSE43922Down-0.0128076843
GSE24585Up0.2101922198
GSE37065Up0.0982433353
GSE28863_A1--
GSE28863_A2--
GSE28863_A3--
GSE28863_A4--
GSE48662Down-0.1834878068

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-215-5pMIMAT0000272MIRT024268MicroarrayFunctional MTI (Weak)19074876
hsa-miR-192-5pMIMAT0000222MIRT026562MicroarrayFunctional MTI (Weak)19074876
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.