HCSGD entry for CORO2B
1. General information
| Official gene symbol | CORO2B |
|---|---|
| Entrez ID | 10391 |
| Gene full name | coronin, actin binding protein, 2B |
| Other gene symbols | CLIPINC |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003779 | Actin binding | NAS | molecular_function |
| GO:0005737 | Cytoplasm | IEA | cellular_component |
| GO:0015629 | Actin cytoskeleton | IBA NAS | cellular_component |
| GO:0016020 | Membrane | NAS | cellular_component |
| GO:0030036 | Actin cytoskeleton organization | IBA NAS | biological_process |
| GO:0051015 | Actin filament binding | IBA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0011466206 | 0.4113074883 | 0.0906312312 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 3.1849232537 |
| GSE13712_SHEAR | Down | -0.1462890594 |
| GSE13712_STATIC | Down | -0.8380680479 |
| GSE19018 | Down | -0.5635693947 |
| GSE19899_A1 | Up | 2.1449365108 |
| GSE19899_A2 | Up | 1.9306735638 |
| PubMed_21979375_A1 | Up | 1.7590875188 |
| PubMed_21979375_A2 | Up | 1.9304857005 |
| GSE35957 | Down | -0.4534492085 |
| GSE36640 | Up | 0.4344192621 |
| GSE54402 | Up | 2.4766556752 |
| GSE9593 | Down | -1.1360588426 |
| GSE43922 | Up | 0.6082846189 |
| GSE24585 | Down | -0.1444470183 |
| GSE37065 | Down | -0.5800410180 |
| GSE28863_A1 | Up | 0.1918569932 |
| GSE28863_A2 | Up | 0.1389816578 |
| GSE28863_A3 | Up | 0.1322186696 |
| GSE28863_A4 | Up | 0.0836543782 |
| GSE48662 | Up | 0.4041733364 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-185-5p | MIMAT0000455 | MIRT004703 | Flow//Immunoblot//Microarray//qRT-PCR | Functional MTI (Weak) | 19688090 |
| hsa-miR-335-5p | MIMAT0000765 | MIRT017553 | Microarray | Functional MTI (Weak) | 18185580 |
| hsa-miR-215-5p | MIMAT0000272 | MIRT024407 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-192-5p | MIMAT0000222 | MIRT026427 | Microarray | Functional MTI (Weak) | 19074876 |
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- mirRecord
- mirRecord
MicroRNA name | mirBase ID | Target site number | MiRNA mature ID | Test method inter | MiRNA regulation site | Reporter target site | Pubmed ID |
|---|---|---|---|---|---|---|---|
| hsa-miR-185-5p | MIMAT0000455 | NA | hsa-miR-185 | 19688090 |
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6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
