HCSGD entry for ABCA7

1. General information

Official gene symbolABCA7
Entrez ID10347
Gene full nameATP-binding cassette, sub-family A (ABC1), member 7
Other gene symbolsABCA-SSN ABCX
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000139Golgi membraneIEAcellular_component
GO:0005215Transporter activityTASmolecular_function
GO:0005524ATP bindingIEAmolecular_function
GO:0005548Phospholipid transporter activityIEAmolecular_function
GO:0005622IntracellularIEAcellular_component
GO:0005737CytoplasmIDAcellular_component
GO:0005794Golgi apparatusIDAcellular_component
GO:0005886Plasma membraneIDA TAScellular_component
GO:0006909PhagocytosisIEAbiological_process
GO:0010008Endosome membraneIEAcellular_component
GO:0016021Integral component of membraneTAScellular_component
GO:0016324Apical plasma membraneIEAcellular_component
GO:0016887ATPase activityIEAmolecular_function
GO:0033700Phospholipid effluxIEAbiological_process
GO:0043190ATP-binding cassette (ABC) transporter complexTAScellular_component
GO:0055085Transmembrane transportTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.22052596410.63937583680.90191752291.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0623248042
GSE13712_SHEARDown-0.6371545977
GSE13712_STATICDown-0.1680510170
GSE19018Up0.0556258267
GSE19899_A1Down-0.2241680767
GSE19899_A2Up0.0042186690
PubMed_21979375_A1Down-0.4542825360
PubMed_21979375_A2Down-0.0687355372
GSE35957Down-0.0185219814
GSE36640Up0.4338416972
GSE54402Down-0.0741275917
GSE9593Up0.2336134576
GSE43922Up0.0377755861
GSE24585Up0.5491167334
GSE37065Down-0.0169828088
GSE28863_A1Up0.0267698851
GSE28863_A2Up0.0487173137
GSE28863_A3Up0.2793529657
GSE28863_A4Up0.1421055582
GSE48662Up1.0544631394

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-335-5pMIMAT0000765MIRT017401MicroarrayFunctional MTI (Weak)18185580
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.