HCSGD entry for TRDN

1. General information

Official gene symbolTRDN
Entrez ID10345
Gene full nametriadin
Other gene symbolsTDN TRISK
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005102Receptor bindingIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005737CytoplasmIDAcellular_component
GO:0005783Endoplasmic reticulumISScellular_component
GO:0005886Plasma membraneIDAcellular_component
GO:0005891Voltage-gated calcium channel complexISScellular_component
GO:0006874Cellular calcium ion homeostasisISSbiological_process
GO:0006936Muscle contractionTASbiological_process
GO:0010649Regulation of cell communication by electrical couplingTASbiological_process
GO:0010880Regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulumISSbiological_process
GO:0014070Response to organic cyclic compoundIEAbiological_process
GO:0014701Junctional sarcoplasmic reticulum membraneISS TAScellular_component
GO:0014808Release of sequestered calcium ion into cytosol by sarcoplasmic reticulumISSbiological_process
GO:0014902Myotube differentiationIEAbiological_process
GO:0016021Integral component of membraneIEA TAScellular_component
GO:0016529Sarcoplasmic reticulumIEA ISScellular_component
GO:0030314Junctional membrane complexISScellular_component
GO:0030674Protein binding, bridgingISSmolecular_function
GO:0031122Cytoplasmic microtubule organizationISSbiological_process
GO:0033017Sarcoplasmic reticulum membraneTAScellular_component
GO:0033018Sarcoplasmic reticulum lumenTAScellular_component
GO:0034220Ion transmembrane transportTASbiological_process
GO:0034704Calcium channel complexISScellular_component
GO:0042803Protein homodimerization activityISSmolecular_function
GO:0044325Ion channel bindingISSmolecular_function
GO:0051279Regulation of release of sequestered calcium ion into cytosolTASbiological_process
GO:0055085Transmembrane transportTASbiological_process
GO:0060047Heart contractionIMPbiological_process
GO:0060315Negative regulation of ryanodine-sensitive calcium-release channel activityTASbiological_process
GO:0060316Positive regulation of ryanodine-sensitive calcium-release channel activityISS TASbiological_process
GO:0086036Regulation of cardiac muscle cell membrane potentialISSbiological_process
GO:0090158Endoplasmic reticulum membrane organizationISSbiological_process
GO:1901846Positive regulation of cell communication by electrical coupling involved in cardiac conductionISSbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.80888663420.77823028380.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0397705732
GSE13712_SHEARDown-0.1475662916
GSE13712_STATICDown-0.0452625887
GSE19018Down-0.1111886965
GSE19899_A1Up0.0980615374
GSE19899_A2Down-0.1113525424
PubMed_21979375_A1Up0.0211186944
PubMed_21979375_A2Up0.2110344227
GSE35957Up0.1667734675
GSE36640Up0.0383814667
GSE54402Down-0.0343111327
GSE9593Down-0.0626750708
GSE43922Up0.0979244152
GSE24585Down-0.2819404825
GSE37065Up0.0447412315
GSE28863_A1Up0.0137385282
GSE28863_A2Up0.0737582003
GSE28863_A3Up0.0719590260
GSE28863_A4Up0.0292797318
GSE48662Up0.0378414939

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-335-5pMIMAT0000765MIRT017167MicroarrayFunctional MTI (Weak)18185580
hsa-miR-148b-3pMIMAT0000759MIRT019248MicroarrayFunctional MTI (Weak)17612493
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.