HCSGD entry for TCIRG1

1. General information

Official gene symbolTCIRG1
Entrez ID10312
Gene full nameT-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3
Other gene symbolsATP6N1C ATP6V0A3 Atp6i OC-116kDa OC116 OPTB1 Stv1 TIRC7 Vph1 a3
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000220Vacuolar proton-transporting V-type ATPase, V0 domainIEAcellular_component
GO:0005215Transporter activityTASmolecular_function
GO:0005739MitochondrionIEAcellular_component
GO:0005765Lysosomal membraneIDAcellular_component
GO:0005886Plasma membraneIEA TAScellular_component
GO:0005887Integral component of plasma membraneTAScellular_component
GO:0006879Cellular iron ion homeostasisTASbiological_process
GO:0006968Cellular defense responseTASbiological_process
GO:0008284Positive regulation of cell proliferationTASbiological_process
GO:0008286Insulin receptor signaling pathwayTASbiological_process
GO:0010008Endosome membraneTAScellular_component
GO:0015078Hydrogen ion transmembrane transporter activityIEAmolecular_function
GO:0015991ATP hydrolysis coupled proton transportIEAbiological_process
GO:0015992Proton transportTASbiological_process
GO:0016324Apical plasma membraneIDAcellular_component
GO:0030670Phagocytic vesicle membraneTAScellular_component
GO:0033179Proton-transporting V-type ATPase, V0 domainIEAcellular_component
GO:0033572Transferrin transportTASbiological_process
GO:0051701Interaction with hostTASbiological_process
GO:0055085Transmembrane transportTASbiological_process
GO:0090382Phagosome maturationTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.21601356710.31993039780.89496192351.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0097418871
GSE13712_SHEARDown-0.2190286304
GSE13712_STATICUp0.0957948965
GSE19018Up0.4251533192
GSE19899_A1Down-0.7487800426
GSE19899_A2Down-0.3928396425
PubMed_21979375_A1Up1.1449221944
PubMed_21979375_A2Up1.0361142034
GSE35957Down-0.7499645589
GSE36640Up0.4241251255
GSE54402Up0.4110374009
GSE9593Down-0.2500067511
GSE43922Down-0.2411442450
GSE24585Up0.2038538037
GSE37065Up0.3059864790
GSE28863_A1Up0.0286023768
GSE28863_A2Down-0.1776040805
GSE28863_A3Up0.0590650666
GSE28863_A4Down-0.0416985397
GSE48662Down-0.1779408820

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.