HCSGD entry for SF3A1
1. General information
| Official gene symbol | SF3A1 |
|---|---|
| Entrez ID | 10291 |
| Gene full name | splicing factor 3a, subunit 1, 120kDa |
| Other gene symbols | PRP21 PRPF21 SAP114 SF3A120 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000389 | MRNA 3'-splice site recognition | TAS | biological_process |
| GO:0000398 | MRNA splicing, via spliceosome | IC IDA TAS | biological_process |
| GO:0003723 | RNA binding | IDA IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005654 | Nucleoplasm | TAS | cellular_component |
| GO:0005681 | Spliceosomal complex | IDA | cellular_component |
| GO:0005684 | U2-type spliceosomal complex | IDA | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0006396 | RNA processing | IEA | biological_process |
| GO:0006397 | MRNA processing | IMP | biological_process |
| GO:0008380 | RNA splicing | TAS | biological_process |
| GO:0010467 | Gene expression | TAS | biological_process |
| GO:0071013 | Catalytic step 2 spliceosome | IDA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.2257890886 | 0.6978227195 | 0.9070243973 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1612803684 |
| GSE13712_SHEAR | Down | -0.1515798744 |
| GSE13712_STATIC | Up | 0.0948713484 |
| GSE19018 | Down | -0.1273833710 |
| GSE19899_A1 | Down | -0.1259231677 |
| GSE19899_A2 | Up | 0.0513800389 |
| PubMed_21979375_A1 | Down | -0.0028142471 |
| PubMed_21979375_A2 | Up | 0.2931620423 |
| GSE35957 | Down | -0.1666197806 |
| GSE36640 | Down | -0.5034920246 |
| GSE54402 | Up | 0.3552190493 |
| GSE9593 | Down | -0.2944683041 |
| GSE43922 | Up | 0.0251738565 |
| GSE24585 | Down | -0.0712029536 |
| GSE37065 | Down | -0.0221042588 |
| GSE28863_A1 | Up | 0.5338634579 |
| GSE28863_A2 | Up | 0.4514477864 |
| GSE28863_A3 | Up | 0.3994437967 |
| GSE28863_A4 | Up | 0.1044792213 |
| GSE48662 | Down | -0.1120767670 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-103a-3p | MIMAT0000101 | MIRT027155 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-744-5p | MIMAT0004945 | MIRT037522 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-615-3p | MIMAT0003283 | MIRT039987 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-193b-3p | MIMAT0002819 | MIRT041239 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-450a-5p | MIMAT0001545 | MIRT042398 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7f-5p | MIMAT0000067 | MIRT051375 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7a-5p | MIMAT0000062 | MIRT052569 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
