HCSGD entry for SMNDC1
1. General information
| Official gene symbol | SMNDC1 |
|---|---|
| Entrez ID | 10285 |
| Gene full name | survival motor neuron domain containing 1 |
| Other gene symbols | SMNR SPF30 TDRD16C |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000375 | RNA splicing, via transesterification reactions | TAS | biological_process |
| GO:0003723 | RNA binding | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | TAS | cellular_component |
| GO:0005681 | Spliceosomal complex | IEA | cellular_component |
| GO:0005737 | Cytoplasm | IEA | cellular_component |
| GO:0006397 | MRNA processing | IEA | biological_process |
| GO:0006915 | Apoptotic process | IEA | biological_process |
| GO:0008380 | RNA splicing | TAS | biological_process |
| GO:0015030 | Cajal body | IEA | cellular_component |
| GO:0016607 | Nuclear speck | IEA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.5066114965 | 0.4656473272 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0814432172 |
| GSE13712_SHEAR | Up | 0.0233529569 |
| GSE13712_STATIC | Up | 0.0861785959 |
| GSE19018 | Down | -0.0890494286 |
| GSE19899_A1 | Up | 0.2807427696 |
| GSE19899_A2 | Up | 0.0728585438 |
| PubMed_21979375_A1 | Up | 0.2022889844 |
| PubMed_21979375_A2 | Down | -0.1702707426 |
| GSE35957 | Down | -0.0814891855 |
| GSE36640 | Down | -0.3651939202 |
| GSE54402 | Up | 0.0855792075 |
| GSE9593 | Down | -0.0761966397 |
| GSE43922 | Up | 0.0071628355 |
| GSE24585 | Down | -0.1028459271 |
| GSE37065 | Up | 0.1562385316 |
| GSE28863_A1 | Up | 0.6039493026 |
| GSE28863_A2 | Up | 0.1400857779 |
| GSE28863_A3 | Up | 0.0160070618 |
| GSE28863_A4 | Down | -0.1610304520 |
| GSE48662 | Down | -0.4007530850 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-26b-5p | MIMAT0000083 | MIRT029377 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-miR-21-5p | MIMAT0000076 | MIRT030868 | Sequencing | Functional MTI (Weak) | 20371350 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
