HCSGD entry for RAMP1
1. General information
| Official gene symbol | RAMP1 |
|---|---|
| Entrez ID | 10267 |
| Gene full name | receptor (G protein-coupled) activity modifying protein 1 |
| Other gene symbols | |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001525 | Angiogenesis | IDA | biological_process |
| GO:0004872 | Receptor activity | IDA | molecular_function |
| GO:0004948 | Calcitonin receptor activity | IDA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005615 | Extracellular space | IEA | cellular_component |
| GO:0005886 | Plasma membrane | IDA TAS | cellular_component |
| GO:0005887 | Integral component of plasma membrane | TAS | cellular_component |
| GO:0006816 | Calcium ion transport | IDA | biological_process |
| GO:0006886 | Intracellular protein transport | IEA | biological_process |
| GO:0007186 | G-protein coupled receptor signaling pathway | IEA | biological_process |
| GO:0008277 | Regulation of G-protein coupled receptor protein signaling pathway | IDA IEA | biological_process |
| GO:0008565 | Protein transporter activity | IDA IEA | molecular_function |
| GO:0009986 | Cell surface | IDA | cellular_component |
| GO:0015026 | Coreceptor activity | IEA | molecular_function |
| GO:0015031 | Protein transport | IDA | biological_process |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0030819 | Positive regulation of cAMP biosynthetic process | IDA | biological_process |
| GO:0031623 | Receptor internalization | IDA IEA | biological_process |
| GO:0031716 | Calcitonin receptor binding | IPI | molecular_function |
| GO:0043235 | Receptor complex | IDA | cellular_component |
| GO:0060050 | Positive regulation of protein glycosylation | IDA | biological_process |
| GO:0072659 | Protein localization to plasma membrane | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.2249210554 | 0.0296785570 | 0.9057752601 | 0.3258945766 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0816963975 |
| GSE13712_SHEAR | Down | -0.1557938940 |
| GSE13712_STATIC | Down | -0.1227391301 |
| GSE19018 | Down | -0.3732241334 |
| GSE19899_A1 | Down | -0.9731867318 |
| GSE19899_A2 | Down | -2.0697661478 |
| PubMed_21979375_A1 | Down | -0.7630884464 |
| PubMed_21979375_A2 | Down | -3.3976811512 |
| GSE35957 | Up | 0.4797974175 |
| GSE36640 | Up | 0.0631859726 |
| GSE54402 | Down | -0.2612653445 |
| GSE9593 | Up | 1.2325619849 |
| GSE43922 | Down | -0.0951501552 |
| GSE24585 | Up | 0.2399249682 |
| GSE37065 | Down | -0.0872440360 |
| GSE28863_A1 | Down | -0.1291048268 |
| GSE28863_A2 | Up | 0.0389114876 |
| GSE28863_A3 | Up | 0.4326417538 |
| GSE28863_A4 | Up | 0.1351535640 |
| GSE48662 | Up | 1.5967042773 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| Pramlintide | DB01278 | - |
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirTarBase
- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
