HCSGD entry for RASGRP2

1. General information

Official gene symbolRASGRP2
Entrez ID10235
Gene full nameRAS guanyl releasing protein 2 (calcium and DAG-regulated)
Other gene symbolsCALDAG-GEFI CDC25L
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001558Regulation of cell growthNASbiological_process
GO:0005085Guanyl-nucleotide exchange factor activityIEA TASmolecular_function
GO:0005509Calcium ion bindingIEA NAS TASmolecular_function
GO:0005622IntracellularIEAcellular_component
GO:0005829CytosolIDA TAScellular_component
GO:0005886Plasma membraneIDAcellular_component
GO:0007165Signal transductionTASbiological_process
GO:0007264Small GTPase mediated signal transductionIEAbiological_process
GO:0007265Ras protein signal transductionNASbiological_process
GO:0007596Blood coagulationTASbiological_process
GO:0008289Lipid bindingTASmolecular_function
GO:0019992Diacylglycerol bindingNASmolecular_function
GO:0030054Cell junctionIEAcellular_component
GO:0030168Platelet activationTASbiological_process
GO:0032587Ruffle membraneIEAcellular_component
GO:0043005Neuron projectionIEAcellular_component
GO:0043087Regulation of GTPase activityTASbiological_process
GO:0045202SynapseIEAcellular_component
GO:0051056Regulation of small GTPase mediated signal transductionIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.67981733220.85343091830.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0731043620
GSE13712_SHEARDown-0.0930440397
GSE13712_STATICDown-0.0943081585
GSE19018Up0.0888972359
GSE19899_A1Up0.0362994547
GSE19899_A2Up0.1245973757
PubMed_21979375_A1Down-0.0080647537
PubMed_21979375_A2Down-0.1664768550
GSE35957Up0.1597272180
GSE36640Up0.1075593985
GSE54402Down-0.0335426798
GSE9593Up0.1654116695
GSE43922Up0.1157629919
GSE24585Up0.1199310742
GSE37065Down-0.0629098369
GSE28863_A1Down-0.2344189637
GSE28863_A2Down-0.0441341659
GSE28863_A3Up0.2070010258
GSE28863_A4Down-0.0411587164
GSE48662Up0.2294101490

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.