HCSGD entry for GDF11
1. General information
| Official gene symbol | GDF11 |
|---|---|
| Entrez ID | 10220 |
| Gene full name | growth differentiation factor 11 |
| Other gene symbols | BMP-11 BMP11 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001501 | Skeletal system development | TAS | biological_process |
| GO:0001656 | Metanephros development | IEA | biological_process |
| GO:0001657 | Ureteric bud development | IEA | biological_process |
| GO:0005125 | Cytokine activity | IEA | molecular_function |
| GO:0005575 | Cellular_component | ND | cellular_component |
| GO:0005576 | Extracellular region | IEA | cellular_component |
| GO:0005615 | Extracellular space | IEA | cellular_component |
| GO:0007399 | Nervous system development | TAS | biological_process |
| GO:0007498 | Mesoderm development | TAS | biological_process |
| GO:0008083 | Growth factor activity | IEA | molecular_function |
| GO:0008285 | Negative regulation of cell proliferation | IEA | biological_process |
| GO:0021512 | Spinal cord anterior/posterior patterning | IEA | biological_process |
| GO:0031016 | Pancreas development | IEA | biological_process |
| GO:0040007 | Growth | IEA | biological_process |
| GO:0045596 | Negative regulation of cell differentiation | IEA | biological_process |
| GO:0048469 | Cell maturation | IEA | biological_process |
| GO:0048593 | Camera-type eye morphogenesis | IEA | biological_process |
Entries Per Page
Displaying Page of
4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.4963632309 | 0.6150999924 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0965002901 |
| GSE13712_SHEAR | Down | -0.2878473819 |
| GSE13712_STATIC | Down | -0.2343140627 |
| GSE19018 | Down | -0.1089931225 |
| GSE19899_A1 | Down | -0.0302249579 |
| GSE19899_A2 | Down | -0.0780565599 |
| PubMed_21979375_A1 | Down | -0.4908913053 |
| PubMed_21979375_A2 | Up | 0.2025056878 |
| GSE35957 | Up | 0.1819175751 |
| GSE36640 | Up | 0.7533637939 |
| GSE54402 | Up | 0.0584806576 |
| GSE9593 | Up | 0.1763645075 |
| GSE43922 | Down | -0.0224006031 |
| GSE24585 | Up | 0.1511029091 |
| GSE37065 | Down | -0.2764922795 |
| GSE28863_A1 | Up | 0.1188530635 |
| GSE28863_A2 | Down | -0.1129526969 |
| GSE28863_A3 | Up | 0.1645259759 |
| GSE28863_A4 | Down | -0.0815747475 |
| GSE48662 | Up | 0.2167412701 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-26b-5p | MIMAT0000083 | MIRT029928 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-miR-423-5p | MIMAT0004748 | MIRT038028 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-615-3p | MIMAT0003283 | MIRT040475 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-18a-3p | MIMAT0002891 | MIRT040960 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-17-5p | MIMAT0000070 | MIRT050946 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7b-5p | MIMAT0000063 | MIRT052163 | CLASH | Functional MTI (Weak) | 23622248 |
Entries Per Page
Displaying Page of
- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
