HCSGD entry for FLOT1
1. General information
| Official gene symbol | FLOT1 |
|---|---|
| Entrez ID | 10211 |
| Gene full name | flotillin 1 |
| Other gene symbols | |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005765 | Lysosomal membrane | IDA | cellular_component |
| GO:0005768 | Endosome | IDA | cellular_component |
| GO:0005815 | Microtubule organizing center | IDA | cellular_component |
| GO:0005901 | Caveola | TAS | cellular_component |
| GO:0007409 | Axonogenesis | IEA | biological_process |
| GO:0008180 | COP9 signalosome | IDA | cellular_component |
| GO:0016021 | Integral component of membrane | TAS | cellular_component |
| GO:0016600 | Flotillin complex | IEA | cellular_component |
| GO:0034451 | Centriolar satellite | IDA | cellular_component |
| GO:0035023 | Regulation of Rho protein signal transduction | IEA | biological_process |
| GO:0035255 | Ionotropic glutamate receptor binding | IEA | molecular_function |
| GO:0042383 | Sarcolemma | IEA | cellular_component |
| GO:0042470 | Melanosome | IEA | cellular_component |
| GO:0045121 | Membrane raft | IDA | cellular_component |
| GO:0072659 | Protein localization to plasma membrane | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9839179552 | 0.0020540139 | 0.9999902473 | 0.0863637380 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.5333305134 |
| GSE13712_SHEAR | Down | -0.6065902730 |
| GSE13712_STATIC | Down | -0.2115246976 |
| GSE19018 | Down | -0.2529203126 |
| GSE19899_A1 | Down | -1.8497040068 |
| GSE19899_A2 | Down | -1.5145522681 |
| PubMed_21979375_A1 | Down | -1.3188579157 |
| PubMed_21979375_A2 | Down | -1.9051239834 |
| GSE35957 | Down | -0.3660501284 |
| GSE36640 | Down | -0.0892009670 |
| GSE54402 | Down | -0.7945055988 |
| GSE9593 | Up | 0.2008411829 |
| GSE43922 | Down | -1.5241852676 |
| GSE24585 | Up | 0.0260189450 |
| GSE37065 | Down | -0.3251652082 |
| GSE28863_A1 | Down | -0.3813058670 |
| GSE28863_A2 | Down | -0.0696917015 |
| GSE28863_A3 | Down | -0.3912357286 |
| GSE28863_A4 | Down | -0.1730074053 |
| GSE48662 | Up | 0.2528688150 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-214-3p | MIMAT0000271 | MIRT024958 | Microarray;Other | Functional MTI (Weak) | 19859982 |
| hsa-miR-484 | MIMAT0002174 | MIRT041850 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-320a | MIMAT0000510 | MIRT044822 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-182-5p | MIMAT0000259 | MIRT047187 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
