HCSGD entry for USPL1
1. General information
| Official gene symbol | USPL1 |
|---|---|
| Entrez ID | 10208 |
| Gene full name | ubiquitin specific peptidase like 1 |
| Other gene symbols | C13orf22 D13S106E RP11-121O19.1 bA121O19.1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004221 | Ubiquitin thiolesterase activity | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0006511 | Ubiquitin-dependent protein catabolic process | IEA | biological_process |
| GO:0008283 | Cell proliferation | IMP | biological_process |
| GO:0015030 | Cajal body | IDA | cellular_component |
| GO:0016926 | Protein desumoylation | IDA | biological_process |
| GO:0030576 | Cajal body organization | IMP | biological_process |
| GO:0032183 | SUMO binding | IDA | molecular_function |
| GO:0043130 | Ubiquitin binding | IDA | molecular_function |
| GO:0070140 | SUMO-specific isopeptidase activity | IDA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.4385911060 | 0.2685156871 | 0.9999902473 | 0.9918048555 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1376621736 |
| GSE13712_SHEAR | Up | 0.3001607243 |
| GSE13712_STATIC | Up | 0.1344895580 |
| GSE19018 | Down | -0.1467723982 |
| GSE19899_A1 | Up | 0.2474108646 |
| GSE19899_A2 | Up | 0.1077262441 |
| PubMed_21979375_A1 | Up | 0.3819982174 |
| PubMed_21979375_A2 | Up | 0.3659505755 |
| GSE35957 | Down | -0.1951433748 |
| GSE36640 | Down | -0.1710705722 |
| GSE54402 | Up | 0.1051346404 |
| GSE9593 | Down | -0.1374240814 |
| GSE43922 | Up | 0.4459349986 |
| GSE24585 | Down | -0.1443667554 |
| GSE37065 | Up | 0.1091888478 |
| GSE28863_A1 | Down | -0.1840531131 |
| GSE28863_A2 | Down | -0.1933908098 |
| GSE28863_A3 | Down | -0.7020740180 |
| GSE28863_A4 | Down | -0.0490395606 |
| GSE48662 | Down | -0.7909287604 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-324-5p | MIMAT0000761 | MIRT043177 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-320a | MIMAT0000510 | MIRT044741 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
