HCSGD entry for PRMT3
1. General information
| Official gene symbol | PRMT3 |
|---|---|
| Entrez ID | 10196 |
| Gene full name | protein arginine methyltransferase 3 |
| Other gene symbols | HRMT1L3 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005737 | Cytoplasm | NAS | cellular_component |
| GO:0005829 | Cytosol | IEA | cellular_component |
| GO:0005840 | Ribosome | IEA | cellular_component |
| GO:0008168 | Methyltransferase activity | IDA | molecular_function |
| GO:0016274 | Protein-arginine N-methyltransferase activity | NAS | molecular_function |
| GO:0031397 | Negative regulation of protein ubiquitination | IDA | biological_process |
| GO:0035242 | Protein-arginine omega-N asymmetric methyltransferase activity | IEA | molecular_function |
| GO:0046872 | Metal ion binding | IEA | molecular_function |
| GO:0072341 | Modified amino acid binding | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.2451366551 | 0.0269126515 | 0.9337542547 | 0.3137899646 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0934888617 |
| GSE13712_SHEAR | Down | -0.3191486581 |
| GSE13712_STATIC | Down | -0.2840475775 |
| GSE19018 | Down | -0.7639311530 |
| GSE19899_A1 | Up | 0.1803109029 |
| GSE19899_A2 | Up | 0.1714518714 |
| PubMed_21979375_A1 | Up | 2.4801747477 |
| PubMed_21979375_A2 | Up | 0.7786337822 |
| GSE35957 | Down | -0.7197930068 |
| GSE36640 | Down | -1.1371528462 |
| GSE54402 | Down | -0.0564445181 |
| GSE9593 | Down | -0.3344930603 |
| GSE43922 | Up | 0.2075855367 |
| GSE24585 | Down | -1.0626596474 |
| GSE37065 | Down | -0.1096089751 |
| GSE28863_A1 | Up | 0.0736184396 |
| GSE28863_A2 | Up | 0.2782168979 |
| GSE28863_A3 | Down | -0.4049283112 |
| GSE28863_A4 | Up | 0.1579974539 |
| GSE48662 | Down | -0.5316465598 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| S-Adenosyl-L-Homocysteine | DB01752 | EXPT02842 |
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-361-3p | MIMAT0004682 | MIRT038276 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-106b-5p | MIMAT0000680 | MIRT044363 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-1260b | MIMAT0015041 | MIRT052756 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
