HCSGD entry for LPCAT3
1. General information
| Official gene symbol | LPCAT3 |
|---|---|
| Entrez ID | 10162 |
| Gene full name | lysophosphatidylcholine acyltransferase 3 |
| Other gene symbols | C3F LPCAT LPLAT 5 LPSAT MBOAT5 OACT5 nessy |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005789 | Endoplasmic reticulum membrane | TAS | cellular_component |
| GO:0006644 | Phospholipid metabolic process | TAS | biological_process |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0016746 | Transferase activity, transferring acyl groups | IEA | molecular_function |
| GO:0036150 | Phosphatidylserine acyl-chain remodeling | TAS | biological_process |
| GO:0036151 | Phosphatidylcholine acyl-chain remodeling | TAS | biological_process |
| GO:0036152 | Phosphatidylethanolamine acyl-chain remodeling | TAS | biological_process |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:0046474 | Glycerophospholipid biosynthetic process | TAS | biological_process |
| GO:0047184 | 1-acylglycerophosphocholine O-acyltransferase activity | IMP | molecular_function |
| GO:0097006 | Regulation of plasma lipoprotein particle levels | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.4169944265 | 0.3294114965 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0480204867 |
| GSE13712_SHEAR | Down | -0.1374093928 |
| GSE13712_STATIC | Up | 0.1253650335 |
| GSE19018 | Down | -0.2624116298 |
| GSE19899_A1 | Down | -0.0794367979 |
| GSE19899_A2 | Down | -0.3035021088 |
| PubMed_21979375_A1 | Up | 0.3633389138 |
| PubMed_21979375_A2 | Down | -0.2702881889 |
| GSE35957 | Up | 0.1119186575 |
| GSE36640 | Up | 0.0598162092 |
| GSE54402 | Up | 0.0249908533 |
| GSE9593 | Up | 0.1558952002 |
| GSE43922 | Down | -0.5489302738 |
| GSE24585 | Up | 0.6614652270 |
| GSE37065 | Up | 0.1405921963 |
| GSE28863_A1 | Down | -0.1338604116 |
| GSE28863_A2 | Up | 0.4413110310 |
| GSE28863_A3 | Down | -0.5303159048 |
| GSE28863_A4 | Up | 0.0320092126 |
| GSE48662 | Up | 0.2274069462 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-98-5p | MIMAT0000096 | MIRT027464 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-let-7b-5p | MIMAT0000063 | MIRT032237 | Proteomics | Functional MTI (Weak) | 18668040 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
