HCSGD entry for EBI3
1. General information
| Official gene symbol | EBI3 |
|---|---|
| Entrez ID | 10148 |
| Gene full name | Epstein-Barr virus induced 3 |
| Other gene symbols | IL-27B IL27B |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004896 | Cytokine receptor activity | IPI | molecular_function |
| GO:0005125 | Cytokine activity | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005615 | Extracellular space | IEA | cellular_component |
| GO:0005886 | Plasma membrane | TAS | cellular_component |
| GO:0006959 | Humoral immune response | TAS | biological_process |
| GO:0007165 | Signal transduction | IPI | biological_process |
| GO:0019221 | Cytokine-mediated signaling pathway | IPI | biological_process |
| GO:0042088 | T-helper 1 type immune response | TAS | biological_process |
| GO:0045078 | Positive regulation of interferon-gamma biosynthetic process | TAS | biological_process |
| GO:0045523 | Interleukin-27 receptor binding | IEA | molecular_function |
| GO:0046641 | Positive regulation of alpha-beta T cell proliferation | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.5896462596 | 0.3746658638 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0493612246 |
| GSE13712_SHEAR | Up | 0.1595339012 |
| GSE13712_STATIC | Up | 0.1345756308 |
| GSE19018 | Up | 0.4197020284 |
| GSE19899_A1 | Down | -0.0059474511 |
| GSE19899_A2 | Up | 0.1269218575 |
| PubMed_21979375_A1 | Down | -0.2179936147 |
| PubMed_21979375_A2 | Down | -0.2677610683 |
| GSE35957 | Up | 0.0454775840 |
| GSE36640 | Up | 0.3517632658 |
| GSE54402 | Down | -0.3125464069 |
| GSE9593 | Down | -0.0347564576 |
| GSE43922 | Up | 0.0375778084 |
| GSE24585 | Up | 0.1029321745 |
| GSE37065 | Down | -0.1371731150 |
| GSE28863_A1 | Down | -0.4641110423 |
| GSE28863_A2 | Down | -0.4895149308 |
| GSE28863_A3 | Up | 0.4057482547 |
| GSE28863_A4 | Up | 0.0813457885 |
| GSE48662 | Up | 0.0090332717 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-324-3p | MIMAT0000762 | MIRT042869 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
