HCSGD entry for YAF2


1. General information

Official gene symbolYAF2
Entrez ID10138
Gene full nameYY1 associated factor 2
Other gene symbols
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0003713Transcription coactivator activityIDAmolecular_function
GO:0003714Transcription corepressor activityIDAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005634NucleusIDAcellular_component
GO:0005730NucleolusIDAcellular_component
GO:0005737CytoplasmIDAcellular_component
GO:0006351Transcription, DNA-templatedIEAbiological_process
GO:0008270Zinc ion bindingIEAmolecular_function
GO:0045892Negative regulation of transcription, DNA-templatedIDAbiological_process
GO:0045893Positive regulation of transcription, DNA-templatedIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.69252804600.38771144330.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0292658224
GSE13712_SHEARDown-0.2821614405
GSE13712_STATICDown-0.2270254654
GSE19018Up0.0197403708
GSE19899_A1Up0.0983736336
GSE19899_A2Up0.1818618382
PubMed_21979375_A1Up0.7535831359
PubMed_21979375_A2Down-0.0088281247
GSE35957Up0.4491159317
GSE36640Up0.0239034465
GSE54402Up0.0344586890
GSE9593Up0.0003683102
GSE43922Up0.0545617545
GSE24585Down-0.1145755003
GSE37065Down-0.0391559736
GSE28863_A1Down-0.2627706662
GSE28863_A2Down-0.4412931413
GSE28863_A3Down-0.5056761139
GSE28863_A4Up0.0348115184
GSE48662Up0.2061342879

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-103a-3pMIMAT0000101MIRT027053SequencingFunctional MTI (Weak)20371350
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.