HCSGD entry for LRPPRC
1. General information
| Official gene symbol | LRPPRC |
|---|---|
| Entrez ID | 10128 |
| Gene full name | leucine-rich pentatricopeptide repeat containing |
| Other gene symbols | CLONE-23970 GP130 LRP130 LSFC |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000794 | Condensed nuclear chromosome | IDA | cellular_component |
| GO:0000961 | Negative regulation of mitochondrial RNA catabolic process | IEA | biological_process |
| GO:0003697 | Single-stranded DNA binding | IEA | molecular_function |
| GO:0003723 | RNA binding | NAS | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005637 | Nuclear inner membrane | IEA | cellular_component |
| GO:0005640 | Nuclear outer membrane | IEA | cellular_component |
| GO:0005654 | Nucleoplasm | IEA | cellular_component |
| GO:0005739 | Mitochondrion | IDA | cellular_component |
| GO:0005856 | Cytoskeleton | IDA | cellular_component |
| GO:0005874 | Microtubule | IDA | cellular_component |
| GO:0006351 | Transcription, DNA-templated | IEA | biological_process |
| GO:0006355 | Regulation of transcription, DNA-templated | IEA | biological_process |
| GO:0008017 | Microtubule binding | TAS | molecular_function |
| GO:0030529 | Ribonucleoprotein complex | IEA | cellular_component |
| GO:0042645 | Mitochondrial nucleoid | IDA | cellular_component |
| GO:0047497 | Mitochondrion transport along microtubule | TAS | biological_process |
| GO:0048471 | Perinuclear region of cytoplasm | IDA | cellular_component |
| GO:0048487 | Beta-tubulin binding | IDA | molecular_function |
| GO:0051015 | Actin filament binding | IDA | molecular_function |
| GO:0051028 | MRNA transport | IEA | biological_process |
| GO:0070129 | Regulation of mitochondrial translation | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.1697465256 | 0.4035481441 | 0.8112320022 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1889010288 |
| GSE13712_SHEAR | Down | -0.1262025601 |
| GSE13712_STATIC | Up | 0.0806643512 |
| GSE19018 | Down | -0.6083876723 |
| GSE19899_A1 | Up | 0.0852036190 |
| GSE19899_A2 | Up | 0.1819791204 |
| PubMed_21979375_A1 | Up | 0.1311754029 |
| PubMed_21979375_A2 | Up | 0.3682391944 |
| GSE35957 | Down | -0.2008429514 |
| GSE36640 | Down | -0.0479475676 |
| GSE54402 | Up | 0.1869811174 |
| GSE9593 | Down | -0.0942117292 |
| GSE43922 | Up | 0.2522898473 |
| GSE24585 | Down | -0.3807519159 |
| GSE37065 | Down | -0.1126763731 |
| GSE28863_A1 | Up | 0.7560722784 |
| GSE28863_A2 | Up | 1.2339405662 |
| GSE28863_A3 | Down | -0.3547398596 |
| GSE28863_A4 | Down | -0.2356621509 |
| GSE48662 | Down | -0.1644493682 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-340-5p | MIMAT0004692 | MIRT019595 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-16-5p | MIMAT0000069 | MIRT031771 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-877-3p | MIMAT0004950 | MIRT036809 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
