HCSGD entry for ACTR1A
1. General information
| Official gene symbol | ACTR1A |
|---|---|
| Entrez ID | 10121 |
| Gene full name | ARP1 actin-related protein 1 homolog A, centractin alpha (yeast) |
| Other gene symbols | ARP1 CTRN1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000086 | G2/M transition of mitotic cell cycle | TAS | biological_process |
| GO:0000278 | Mitotic cell cycle | TAS | biological_process |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005737 | Cytoplasm | IDA IEA | cellular_component |
| GO:0005813 | Centrosome | IDA | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0005856 | Cytoskeleton | IEA | cellular_component |
| GO:0005869 | Dynactin complex | TAS | cellular_component |
| GO:0005875 | Microtubule associated complex | TAS | cellular_component |
| GO:0016192 | Vesicle-mediated transport | TAS | biological_process |
| GO:0019886 | Antigen processing and presentation of exogenous peptide antigen via MHC class II | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.2854154059 | 0.6360417727 | 0.9847186918 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.2692108655 |
| GSE13712_SHEAR | Down | -0.1716166619 |
| GSE13712_STATIC | Down | -0.1191954377 |
| GSE19018 | Up | 0.4818038647 |
| GSE19899_A1 | Down | -0.3489110174 |
| GSE19899_A2 | Up | 0.2782094173 |
| PubMed_21979375_A1 | Up | 0.1618564917 |
| PubMed_21979375_A2 | Up | 0.2787029535 |
| GSE35957 | Down | -0.0736220898 |
| GSE36640 | Up | 0.3139127845 |
| GSE54402 | Up | 0.1811915355 |
| GSE9593 | Up | 0.0237058049 |
| GSE43922 | Up | 0.1125516290 |
| GSE24585 | Down | -0.2397368412 |
| GSE37065 | Down | -0.1509002069 |
| GSE28863_A1 | Down | -0.0948240773 |
| GSE28863_A2 | Up | 0.1011324386 |
| GSE28863_A3 | Down | -0.5387728145 |
| GSE28863_A4 | Up | 0.0227713848 |
| GSE48662 | Up | 0.0742844786 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-16-5p | MIMAT0000069 | MIRT000805 | proteomics analysis | Functional MTI (Weak) | 18362358 |
| hsa-miR-15a-5p | MIMAT0000068 | MIRT000806 | proteomics analysis | Functional MTI (Weak) | 18362358 |
| hsa-miR-148a-5p | MIMAT0004549 | MIRT038705 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-193b-3p | MIMAT0002819 | MIRT041381 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-331-3p | MIMAT0000760 | MIRT043350 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-210-3p | MIMAT0000267 | MIRT047006 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-92a-3p | MIMAT0000092 | MIRT049187 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
- mirRecord
MicroRNA name | mirBase ID | Target site number | MiRNA mature ID | Test method inter | MiRNA regulation site | Reporter target site | Pubmed ID |
|---|---|---|---|---|---|---|---|
| hsa-miR-16-5p | MIMAT0000069 | NA | hsa-miR-16 | proteomics analysis | overexpression | 18362358 | |
| hsa-miR-15a-5p | MIMAT0000068 | NA | hsa-miR-15a | proteomics analysis | overexpression | 18362358 |
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6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
