HCSGD entry for FEM1B
1. General information
| Official gene symbol | FEM1B |
|---|---|
| Entrez ID | 10116 |
| Gene full name | fem-1 homolog b (C. elegans) |
| Other gene symbols | F1A-ALPHA FIAA |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004842 | Ubiquitin-protein ligase activity | IMP | molecular_function |
| GO:0005123 | Death receptor binding | IMP NAS | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0006915 | Apoptotic process | NAS | biological_process |
| GO:0016567 | Protein ubiquitination | IEA | biological_process |
| GO:0051438 | Regulation of ubiquitin-protein ligase activity | IMP | biological_process |
| GO:0060442 | Branching involved in prostate gland morphogenesis | IEA | biological_process |
| GO:0060743 | Epithelial cell maturation involved in prostate gland development | IEA | biological_process |
| GO:1902041 | Regulation of extrinsic apoptotic signaling pathway via death domain receptors | IMP | biological_process |
| GO:2000001 | Regulation of DNA damage checkpoint | IMP | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.4546253258 | 0.3350371528 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.6597989813 |
| GSE13712_SHEAR | Up | 0.2187137871 |
| GSE13712_STATIC | Down | -0.0660230691 |
| GSE19018 | Down | -0.2136834202 |
| GSE19899_A1 | Up | 0.0444995975 |
| GSE19899_A2 | Up | 0.0604511393 |
| PubMed_21979375_A1 | Up | 0.3982088531 |
| PubMed_21979375_A2 | Up | 0.4964037952 |
| GSE35957 | Up | 0.3642654839 |
| GSE36640 | Up | 0.0042141913 |
| GSE54402 | Up | 0.0679435682 |
| GSE9593 | Down | -0.0207539169 |
| GSE43922 | Down | -0.0133619998 |
| GSE24585 | Up | 0.1569553412 |
| GSE37065 | Up | 0.2801429931 |
| GSE28863_A1 | Down | -0.0286973422 |
| GSE28863_A2 | Up | 0.0145304352 |
| GSE28863_A3 | Down | -0.6769201759 |
| GSE28863_A4 | Up | 0.0715008848 |
| GSE48662 | Down | -0.2580055087 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-186-5p | MIMAT0000456 | MIRT044948 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-30b-5p | MIMAT0000420 | MIRT046117 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-10b-5p | MIMAT0000254 | MIRT047427 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-10a-5p | MIMAT0000253 | MIRT047584 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-30d-5p | MIMAT0000245 | MIRT047779 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-30c-5p | MIMAT0000244 | MIRT047848 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
