HCSGD entry for ARPC3
1. General information
| Official gene symbol | ARPC3 |
|---|---|
| Entrez ID | 10094 |
| Gene full name | actin related protein 2/3 complex, subunit 3, 21kDa |
| Other gene symbols | ARC21 p21-Arc |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003779 | Actin binding | IEA | molecular_function |
| GO:0005200 | Structural constituent of cytoskeleton | TAS | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0005885 | Arp2/3 protein complex | IEA | cellular_component |
| GO:0006928 | Cellular component movement | TAS | biological_process |
| GO:0015629 | Actin cytoskeleton | TAS | cellular_component |
| GO:0030027 | Lamellipodium | IEA | cellular_component |
| GO:0034314 | Arp2/3 complex-mediated actin nucleation | IEA | biological_process |
| GO:0038096 | Fc-gamma receptor signaling pathway involved in phagocytosis | TAS | biological_process |
| GO:0045087 | Innate immune response | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.5274527716 | 0.6493361498 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1146174028 |
| GSE13712_SHEAR | Up | 0.4147437647 |
| GSE13712_STATIC | Up | 0.2800993985 |
| GSE19018 | Up | 0.0619978212 |
| GSE19899_A1 | Up | 0.1873929660 |
| GSE19899_A2 | Up | 0.2825638954 |
| PubMed_21979375_A1 | Up | 0.1475124786 |
| PubMed_21979375_A2 | Down | -0.0846236239 |
| GSE35957 | Down | -0.2669916133 |
| GSE36640 | Up | 0.2111863072 |
| GSE54402 | Up | 0.1607338270 |
| GSE9593 | Up | 0.0868564046 |
| GSE43922 | Down | -0.0733950811 |
| GSE24585 | Up | 0.0695625973 |
| GSE37065 | Down | -0.2080125318 |
| GSE28863_A1 | Down | -0.2268579185 |
| GSE28863_A2 | Down | -0.0756581150 |
| GSE28863_A3 | Down | -0.2653942368 |
| GSE28863_A4 | Up | 0.0072605932 |
| GSE48662 | Down | -0.3209804842 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| N-[2-(2-methyl-1H-indol-3-yl)ethyl]thiophene-2-carboxamide | DB08235 | - |
| (2S)-2-(3-bromophenyl)-3-(5-chloro-2-hydroxyphenyl)-1,3-thiazolidin-4-one | DB08236 | - |
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-155-5p | MIMAT0000646 | MIRT020984 | Reporter assay;Other | Non-Functional MTI | 20584899 |
| hsa-miR-25-3p | MIMAT0000081 | MIRT050237 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
