HCSGD entry for USH1C

1. General information

Official gene symbolUSH1C
Entrez ID10083
Gene full nameUsher syndrome 1C (autosomal recessive, severe)
Other gene symbolsAIE-75 DFNB18 DFNB18A NY-CO-37 NY-CO-38 PDZ-45 PDZ-73 PDZ-73/NY-CO-38 PDZ73 ush1cpst
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000086G2/M transition of mitotic cell cycleIMPbiological_process
GO:0001750Photoreceptor outer segmentIEAcellular_component
GO:0001917Photoreceptor inner segmentIEAcellular_component
GO:0005515Protein bindingIPImolecular_function
GO:0005737CytoplasmIDAcellular_component
GO:0005829CytosolIEAcellular_component
GO:0005856CytoskeletonIEAcellular_component
GO:0005886Plasma membraneIEAcellular_component
GO:0007605Sensory perception of soundIMPbiological_process
GO:0030046Parallel actin filament bundle assemblyIEAbiological_process
GO:0032420StereociliumTAScellular_component
GO:0042472Inner ear morphogenesisIEAbiological_process
GO:0042491Auditory receptor cell differentiationIEAbiological_process
GO:0045177Apical part of cellIDAcellular_component
GO:0045202SynapseIEAcellular_component
GO:0045494Photoreceptor cell maintenanceIMPbiological_process
GO:0050953Sensory perception of light stimulusIMPbiological_process
GO:0050957EquilibrioceptionIMPbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.56008582500.89855902130.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0374171742
GSE13712_SHEARUp0.0026631833
GSE13712_STATICUp0.1083752915
GSE19018Up0.0224624978
GSE19899_A1Up0.0942841958
GSE19899_A2Up0.1838398089
PubMed_21979375_A1Up0.0177516019
PubMed_21979375_A2Down-0.0699951171
GSE35957Up0.2378714544
GSE36640Up0.0629491430
GSE54402Down-0.0052747191
GSE9593Down-0.0920214779
GSE43922Up0.0878026732
GSE24585Up0.0812502788
GSE37065Down-0.0262811805
GSE28863_A1Down-0.0387780076
GSE28863_A2Down-0.0036453544
GSE28863_A3Up0.3516218031
GSE28863_A4Up0.0422679429
GSE48662Down-0.0471276080

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-335-5pMIMAT0000765MIRT016712MicroarrayFunctional MTI (Weak)18185580
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.