HCSGD entry for SH2D3A
1. General information
| Official gene symbol | SH2D3A |
|---|---|
| Entrez ID | 10045 |
| Gene full name | SH2 domain containing 3A |
| Other gene symbols | NSP1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005070 | SH3/SH2 adaptor activity | TAS | molecular_function |
| GO:0005085 | Guanyl-nucleotide exchange factor activity | IEA | molecular_function |
| GO:0005622 | Intracellular | IEA | cellular_component |
| GO:0007254 | JNK cascade | TAS | biological_process |
| GO:0007264 | Small GTPase mediated signal transduction | IEA | biological_process |
| GO:0009967 | Positive regulation of signal transduction | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.7526543444 | 0.7913302192 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0645927200 |
| GSE13712_SHEAR | Up | 0.1013598034 |
| GSE13712_STATIC | Up | 0.1294476285 |
| GSE19018 | Up | 0.0555135989 |
| GSE19899_A1 | Up | 0.0241081671 |
| GSE19899_A2 | Up | 0.2258221623 |
| PubMed_21979375_A1 | Down | -0.3578040826 |
| PubMed_21979375_A2 | Down | -0.1151075268 |
| GSE35957 | Down | -0.0468552804 |
| GSE36640 | Up | 0.2469590832 |
| GSE54402 | Down | -0.0402803355 |
| GSE9593 | Up | 0.0098806491 |
| GSE43922 | Up | 0.0444654296 |
| GSE24585 | Up | 0.0071749955 |
| GSE37065 | Up | 0.0559693941 |
| GSE28863_A1 | Down | -0.1344204111 |
| GSE28863_A2 | Down | -0.1216407965 |
| GSE28863_A3 | Up | 0.1973219899 |
| GSE28863_A4 | Up | 0.0681883386 |
| GSE48662 | Down | -0.0879981470 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT016816 | Microarray | Functional MTI (Weak) | 18185580 |
| hsa-miR-124-3p | MIMAT0000422 | MIRT022136 | Microarray | Functional MTI (Weak) | 18668037 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
