HCSGD entry for TOM1L1
1. General information
| Official gene symbol | TOM1L1 |
|---|---|
| Entrez ID | 10040 |
| Gene full name | target of myb1 (chicken)-like 1 |
| Other gene symbols | OK/KNS-CL.3 SRCASM |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005622 | Intracellular | IEA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005764 | Lysosome | TAS | cellular_component |
| GO:0005768 | Endosome | IDA | cellular_component |
| GO:0005795 | Golgi stack | IEA | cellular_component |
| GO:0005829 | Cytosol | IDA | cellular_component |
| GO:0006886 | Intracellular protein transport | IEA | biological_process |
| GO:0007165 | Signal transduction | IDA | biological_process |
| GO:0010008 | Endosome membrane | IEA | cellular_component |
| GO:0017124 | SH3 domain binding | IEA | molecular_function |
| GO:0019901 | Protein kinase binding | IPI | molecular_function |
| GO:0030276 | Clathrin binding | IDA | molecular_function |
| GO:0030295 | Protein kinase activator activity | IEA | molecular_function |
| GO:0031954 | Positive regulation of protein autophosphorylation | IDA | biological_process |
| GO:0032147 | Activation of protein kinase activity | IDA | biological_process |
| GO:0043130 | Ubiquitin binding | TAS | molecular_function |
| GO:0043162 | Ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway | NAS | biological_process |
| GO:0045839 | Negative regulation of mitosis | IDA | biological_process |
| GO:2000278 | Regulation of DNA biosynthetic process | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.1227459975 | 0.1242768778 | 0.7164122395 | 0.6773151139 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0810201117 |
| GSE13712_SHEAR | Up | 2.0496376797 |
| GSE13712_STATIC | Up | 1.9987025888 |
| GSE19018 | Down | -0.2986713210 |
| GSE19899_A1 | Down | -0.0672794958 |
| GSE19899_A2 | Down | -0.1350211448 |
| PubMed_21979375_A1 | Up | 1.3212589604 |
| PubMed_21979375_A2 | Up | 0.0550515040 |
| GSE35957 | Down | -1.3616049185 |
| GSE36640 | Down | -0.1067956968 |
| GSE54402 | Up | 0.1244078407 |
| GSE9593 | Down | -0.1021744724 |
| GSE43922 | Down | -0.2853293527 |
| GSE24585 | Down | -0.0443324148 |
| GSE37065 | Down | -0.0061540138 |
| GSE28863_A1 | Down | -0.1858239043 |
| GSE28863_A2 | Down | -0.2842965924 |
| GSE28863_A3 | Down | -0.4211851243 |
| GSE28863_A4 | Up | 0.2368760460 |
| GSE48662 | Down | -0.3966589658 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-124-3p | MIMAT0000422 | MIRT002599 | Microarray//Microarray;Other | Functional MTI (Weak) | 15685193 |
| hsa-miR-92a-3p | MIMAT0000092 | MIRT049735 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
