HCSGD entry for CDH6
1. General information
| Official gene symbol | CDH6 |
|---|---|
| Entrez ID | 1004 |
| Gene full name | cadherin 6, type 2, K-cadherin (fetal kidney) |
| Other gene symbols | CAD6 KCAD |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005509 | Calcium ion binding | IEA | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005886 | Plasma membrane | IDA TAS | cellular_component |
| GO:0007155 | Cell adhesion | TAS | biological_process |
| GO:0007156 | Homophilic cell adhesion | IEA | biological_process |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0034329 | Cell junction assembly | TAS | biological_process |
| GO:0034332 | Adherens junction organization | TAS | biological_process |
| GO:0045216 | Cell-cell junction organization | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0596133012 | 0.0065207325 | 0.5288445231 | 0.1636646226 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.3621356274 |
| GSE13712_SHEAR | Down | -0.1424855696 |
| GSE13712_STATIC | Down | -0.2672124942 |
| GSE19018 | Down | -0.9058691790 |
| GSE19899_A1 | Down | -0.6075269849 |
| GSE19899_A2 | Down | -3.5886262697 |
| PubMed_21979375_A1 | Down | -4.5298844582 |
| PubMed_21979375_A2 | Down | -4.0157076504 |
| GSE35957 | Up | 0.4100630206 |
| GSE36640 | Up | 0.6846634402 |
| GSE54402 | Up | 0.4074555276 |
| GSE9593 | Down | -0.0092851425 |
| GSE43922 | Down | -1.3122758826 |
| GSE24585 | Down | -0.0345129812 |
| GSE37065 | Up | 0.2553488273 |
| GSE28863_A1 | Up | 0.8851676592 |
| GSE28863_A2 | Up | 0.9599492328 |
| GSE28863_A3 | Up | 0.4624225053 |
| GSE28863_A4 | Up | 0.4521563302 |
| GSE48662 | Down | -0.3633445757 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-155-5p | MIMAT0000646 | MIRT020970 | Proteomics | Functional MTI (Weak) | 20584899 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: 1 abstracts the gene occurs.
PubMed ID of the article | Sentenece the gene occurs |
|---|---|
| 20622962 | Quantitative real-time PCR validated the microarray data for selected genes: markedly increased genes were CXCL12, cadherin 6 (CDH6), and folate receptor 3 (FOLR3) |
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